{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T12:59:06Z","timestamp":1793105946737,"version":"4.5.0"},"reference-count":28,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2025,5,5]],"date-time":"2025-05-05T00:00:00Z","timestamp":1746403200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,5,5]],"date-time":"2025-05-05T00:00:00Z","timestamp":1746403200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Cereb Blood Flow Metab"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:p>The Circle of Willis (CW), visualized via Magnetic Resonance Angiography (MRA), is crucial for assessing cerebral circulation. Accurate artery identification is essential not only for detecting stenosis and pathological changes but also for understanding vascular adaptations in healthy aging. Manual CW assessment is time-consuming, necessitating automated alternatives. This study evaluates intracranial artery diameter estimations from the Express IntraCranial Arteries Breakdown (eICAB) toolbox against manual measurements. eICAB was tested on 631 participants from the Northern Manhattan Study (NOMAS) with 1.5T MRA images (0.293\u2009\u00d7\u20090.293\u2009\u00d7\u20091\u2009mm resolution). We analyzed eICAB\u2019s detection and diameter estimation accuracy of the Internal Carotid (ICA), Basilar (BA), Anterior Cerebral (ACA), Middle Cerebral (MCA), Posterior Cerebral (PCA), and Posterior Communicating (PCom). eICAB showed over 95% accuracy in detecting major arteries except for PCA and PCom (\u223c80%). Diameter discrepancies were generally \u22640.5\u2009mm, with ICA and BA reaching 1\u2009mm. Spearman correlation (p\u2009\u226a\u20090.05) confirmed strong agreement between automated and manual measurements. Resampling at 0.2083\u2009mm improved precision. eICAB accurately identifies CW arteries and estimates diameters, demonstrating strong clinical and research potential.<\/jats:p>","DOI":"10.1177\/0271678x251338972","type":"journal-article","created":{"date-parts":[[2025,5,5]],"date-time":"2025-05-05T07:18:57Z","timestamp":1746429537000},"page":"1774-1784","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Accurate and fully automated diameter measurements of Circle of Willis arteries on MRA imaging"],"prefix":"10.1177","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5701-8506","authenticated-orcid":false,"given":"Julia","family":"Huck","sequence":"first","affiliation":[{"name":"Department of Nuclear Medicine and Radiobiology, Universit\u00e9 de Sherbrooke, Sherbrooke, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davy","family":"Vanderweyen","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine and Radiobiology, Universit\u00e9 de Sherbrooke, Sherbrooke, CA, USA"},{"name":"Department of Diagnostic Radiology, Universit\u00e9 de Sherbrooke, Sherbrooke, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatjana","family":"Rundek","sequence":"additional","affiliation":[{"name":"Evelyn F. 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