{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T08:05:08Z","timestamp":1789286708888,"version":"build-2803163510"},"reference-count":89,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T00:00:00Z","timestamp":1780531200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T00:00:00Z","timestamp":1780531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Royal Society Wolfson Research Fellowship","award":["WM170007"],"award-info":[{"award-number":["WM170007"]}]},{"DOI":"10.13039\/501100000383","name":"higher education funding council for wales","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000383","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001665","name":"agence nationale de la recherche","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100031366","name":"era-net neuron","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100031366","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007546","name":"ANSES","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100007546","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100008222","name":"universit\u00e9 de montpellier","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008222","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002744","name":"bar-ilan university","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002744","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Cereb Blood Flow Metab"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:p>\n                    A network physiology framework investigated how coordinated interactions among multiple organ systems collectively support the preservation of cerebral bioenergetic function and better distinguish adaptive from maladaptive responses to hypoxia. Twelve healthy males were passively exposed to 6 h of normoxia (21% O\n                    <jats:sub>2<\/jats:sub>\n                    ) and hypoxia (12% O\n                    <jats:sub>2<\/jats:sub>\n                    ) in a randomised, single-blind, crossover design. Venous blood was assayed for oxidative-nitrosative stress (OXNOS, spectroscopy\/chemiluminescence) and neurovascular unit (hs-ELISA) biomarkers. Global cerebral delivery of O\n                    <jats:sub>2<\/jats:sub>\n                    and glucose were determined by duplex ultrasound. Clinical acute mountain sickness (AMS+) was diagnosed in five participants. Cerebral substrate delivery was well maintained in both hypoxia and AMS+ (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    &lt; 0.05 vs normoxia and AMS\u2212) despite marked arterial hypoxemia. Bioenergetic defence coincided with pronounced elevations in the spectral amplitude and phase synchronisation of very low-frequency oscillations (VLFOs, 0.03\u20130.06 Hz), which were evident across multiple organ systems and most prominent within the cerebral network. Systemic VLFOs were further exaggerated and more functionally connected in AMS+ in the absence of exaggerated systemic OXNOS or structural damage\/destabilisation of the neurovascular unit (both\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    &lt; 0.05 vs normoxia and AMS\u2212). Collectively, these findings suggest that AMS, while characterised by debilitating symptomatology, may reflect a neuroprotective adaptive as opposed to pathologically maladaptive phenotype.\n                  <\/jats:p>","DOI":"10.1177\/0271678x261447119","type":"journal-article","created":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T09:22:20Z","timestamp":1780564940000},"page":"2393-2410","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Network oscillatory dynamics accompany cerebral bioenergetic defence in hypoxia"],"prefix":"10.1177","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0498-7095","authenticated-orcid":false,"given":"Damian M","family":"Bailey","sequence":"first","affiliation":[{"name":"Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Pontypridd, UK"},{"name":"Bexorg, Inc., New Haven, CT, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1005-7038","authenticated-orcid":false,"given":"Benjamin S","family":"Stacey","sequence":"additional","affiliation":[{"name":"Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Pontypridd, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaopeng","family":"Ma","sequence":"additional","affiliation":[{"name":"Keck Laboratory for Network Physiology, Department of Physics, Boston University, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuro","family":"Washio","sequence":"additional","affiliation":[{"name":"Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, The University of Texas Southwestern Medical Center, Dallas, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5512-0497","authenticated-orcid":false,"given":"Hayato","family":"Tsukamoto","sequence":"additional","affiliation":[{"name":"Faculty of Sport Sciences, Waseda University, Tokorozawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0097-0616","authenticated-orcid":false,"given":"Thomas S","family":"Owens","sequence":"additional","affiliation":[{"name":"Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Pontypridd, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas A","family":"Calverley","sequence":"additional","affiliation":[{"name":"Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Pontypridd, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lewis","family":"Fall","sequence":"additional","affiliation":[{"name":"Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Pontypridd, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6757-6448","authenticated-orcid":false,"given":"Christopher J","family":"Marley","sequence":"additional","affiliation":[{"name":"Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Pontypridd, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelo","family":"Iannetelli","sequence":"additional","affiliation":[{"name":"Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Pontypridd, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Hashimoto","sequence":"additional","affiliation":[{"name":"Faculty of Sport and Health Science, Ritsumeikan University, Shiga, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0896-7008","authenticated-orcid":false,"given":"Soichi","family":"Ando","sequence":"additional","affiliation":[{"name":"Graduate School of Informatics and Engineering, The University of Electro-Communications, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5297-6468","authenticated-orcid":false,"given":"Shigehiko","family":"Ogoh","sequence":"additional","affiliation":[{"name":"Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Pontypridd, UK"},{"name":"Department of Biomedical Engineering, Toyo University, Asaka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"Marchi","sequence":"additional","affiliation":[{"name":"CNRS 5203, INSERM U1191, Institute of Functional Genomics, University of Montpellier, Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josip","family":"Butkovic","sequence":"additional","affiliation":[{"name":"Bexorg, Inc., New Haven, CT, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan","family":"Mumlek","sequence":"additional","affiliation":[{"name":"Bexorg, Inc., New Haven, CT, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brad","family":"Parry","sequence":"additional","affiliation":[{"name":"Bexorg, Inc., New Haven, CT, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zvonimir","family":"Vrselja","sequence":"additional","affiliation":[{"name":"Bexorg, Inc., New Haven, CT, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James A","family":"Pawelczyk","sequence":"additional","affiliation":[{"name":"Noll Laboratory, Department of Kinesiology, Pennsylvania State University, University Park, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronny P","family":"Bartsch","sequence":"additional","affiliation":[{"name":"Department of Physics, Bar-Ilan-University, Ramat Gan, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,6,4]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1113\/JP276814"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1113\/EP088005"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X251329707"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI101995"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2013.268953"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X251322348"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI102150"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1113\/JP281517"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1089\/ham.2016.0081"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-009-0145-9"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200107123450206"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1183\/16000617.0096-2016"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00861.2019"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2008.159855"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00366.2009"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms1705"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.3389\/fnetp.2021.711778"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.2471\/BLT.08.050955"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1113\/JP276898"},{"key":"e_1_3_3_21_2","first-page":"1","article-title":"Post-prandial hyperlipidaemia impairs systemic vascular function and dynamic cerebral autoregulation in young and old male adults","volume":"2","author":"Marley CJ","year":"2025","unstructured":"Marley CJ, Davis D, Brugniaux JV, et al. Post-prandial hyperlipidaemia impairs systemic vascular function and dynamic cerebral autoregulation in young and old male adults. J Nutr Physiol 2025; 2: 1\u20137.","journal-title":"J Nutr Physiol"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1681.1997.tb01212.x"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1113\/EP089660"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1113\/EP091245"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1007\/s13105-012-0149-z"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bja.2018.02.062"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2020.05.048"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2018.05.090"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.116.024226"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M501179200"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-59745-129-1_2"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2020.577312"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1111\/jnc.14574"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X221075967"},{"issue":"2","key":"e_1_3_3_35_2","first-page":"127","article-title":"Purification and characterization of human neuron-specific enolase: radioimmunoassay development","volume":"5","author":"Pahlman S","year":"1984","unstructured":"Pahlman S, Esscher T, Bergvall P, et al. Purification and characterization of human neuron-specific enolase: radioimmunoassay development. Tumour Biol 1984; 5(2): 127\u2013139.","journal-title":"Tumour Biol"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1993.74.5.2566"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.2001.91.2.929"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2012.228551"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.1113\/EP089196"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.1089\/ham.2017.0164"},{"issue":"12","key":"e_1_3_3_41_2","first-page":"1063","article-title":"Procedures for the measurement of acute mountain sickness","volume":"54","author":"Sampson JB","year":"1983","unstructured":"Sampson JB, Cymerman A, Burse RL, et al. Procedures for the measurement of acute mountain sickness. Aviat Space Environ Med 1983; 54(12 Pt 1): 1063\u20131073.","journal-title":"Aviat Space Environ Med"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3959(89)90067-5"},{"key":"e_1_3_3_43_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jcbfm.9600169"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0142143"},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1383-8121(01)80012-9"},{"issue":"6","key":"e_1_3_3_46_2","article-title":"Spurious detection of phase synchronization in coupled nonlinear oscillators","volume":"73","author":"Xu L","year":"2006","unstructured":"Xu L, Chen Z, Hu K, et al. Spurious detection of phase synchronization in coupled nonlinear oscillators. Phys Rev E 2006; 73(6 Pt 2): 065201.","journal-title":"Phys Rev E"},{"key":"e_1_3_3_47_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41592-019-0686-2"},{"key":"e_1_3_3_48_2","doi-asserted-by":"publisher","DOI":"10.1113\/EP088755"},{"key":"e_1_3_3_49_2","doi-asserted-by":"publisher","DOI":"10.1113\/JP288939"},{"issue":"149","key":"e_1_3_3_50_2","first-page":"1","article-title":"Continuous recording and control of ventricular fluid pressure in neurosurgical practice","volume":"36","author":"Lundberg N","year":"1960","unstructured":"Lundberg N. Continuous recording and control of ventricular fluid pressure in neurosurgical practice. Acta Psychiatr Scand Suppl 1960; 36(149): 1\u2013193.","journal-title":"Acta Psychiatr Scand Suppl"},{"key":"e_1_3_3_51_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02343541"},{"key":"e_1_3_3_52_2","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvz327"},{"key":"e_1_3_3_53_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.85.1.164"},{"key":"e_1_3_3_54_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00702-007-0825-2"},{"key":"e_1_3_3_55_2","doi-asserted-by":"publisher","DOI":"10.1186\/s40659-021-00362-2"},{"key":"e_1_3_3_56_2","first-page":"139","article-title":"Slow rhythmic oscillations in intracranial CSF and blood flow: registered by MRI","volume":"81","author":"Strik C","year":"2002","unstructured":"Strik C, Klose U, Kiefer C, et al. Slow rhythmic oscillations in intracranial CSF and blood flow: registered by MRI. Acta Neurochir Suppl 2002; 81: 139\u2013142.","journal-title":"Acta Neurochir Suppl"},{"key":"e_1_3_3_57_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910340409"},{"key":"e_1_3_3_58_2","doi-asserted-by":"publisher","DOI":"10.1113\/JP282605"},{"issue":"3","key":"e_1_3_3_59_2","article-title":"Hemodynamic fluctuations and baroreflex sensitivity in humans: a beat-to-beat model","volume":"253","author":"deBoer RW","year":"1987","unstructured":"deBoer RW, Karemaker JM, Strackee J. Hemodynamic fluctuations and baroreflex sensitivity in humans: a beat-to-beat model. Am J Physiol 1987; 253(3 Pt 2): H680\u2013H689.","journal-title":"Am J Physiol"},{"key":"e_1_3_3_60_2","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.90822.2008"},{"key":"e_1_3_3_61_2","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00022.2020"},{"key":"e_1_3_3_62_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-024-07108-6"},{"key":"e_1_3_3_63_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.2000.279.2.H550"},{"key":"e_1_3_3_64_2","doi-asserted-by":"publisher","DOI":"10.3389\/fnetp.2024.1438073"},{"key":"e_1_3_3_65_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.aax5440"},{"key":"e_1_3_3_66_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1241224"},{"key":"e_1_3_3_67_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00021.2023"},{"key":"e_1_3_3_68_2","doi-asserted-by":"publisher","DOI":"10.1113\/JP284579"},{"issue":"1","key":"e_1_3_3_69_2","first-page":"75","article-title":"Evidence of flowmotion induced changes in local tissue oxygenation","volume":"12","author":"Tsai AG","year":"1993","unstructured":"Tsai AG, Intaglietta M. Evidence of flowmotion induced changes in local tissue oxygenation. Int J Microcirc Clin Exp 1993; 12(1): 75\u201388.","journal-title":"Int J Microcirc Clin Exp"},{"key":"e_1_3_3_70_2","doi-asserted-by":"publisher","DOI":"10.1006\/jtbi.2000.2254"},{"key":"e_1_3_3_71_2","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X231169579"},{"key":"e_1_3_3_72_2","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00293.2017"},{"key":"e_1_3_3_73_2","doi-asserted-by":"publisher","DOI":"10.1089\/ham.2005.6.289"},{"key":"e_1_3_3_74_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.108.543959"},{"key":"e_1_3_3_75_2","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X251313747"},{"key":"e_1_3_3_76_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00148.2004"},{"key":"e_1_3_3_77_2","doi-asserted-by":"publisher","DOI":"10.1021\/jp025518z"},{"key":"e_1_3_3_78_2","doi-asserted-by":"publisher","DOI":"10.1080\/10739680601139179"},{"key":"e_1_3_3_79_2","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X251399120"},{"key":"e_1_3_3_80_2","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X251320902"},{"issue":"1","key":"e_1_3_3_81_2","first-page":"3","article-title":"Heart rate variability as a biomarker for epilepsy seizure prediction","volume":"118","author":"Moridani MK","year":"2017","unstructured":"Moridani MK, Farhadi H. Heart rate variability as a biomarker for epilepsy seizure prediction. Bratisl Lek Listy 2017; 118(1): 3\u20138.","journal-title":"Bratisl Lek Listy"},{"key":"e_1_3_3_82_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1038-16.2016"},{"key":"e_1_3_3_83_2","doi-asserted-by":"publisher","DOI":"10.3389\/fnetp.2023.1335808"},{"key":"e_1_3_3_84_2","doi-asserted-by":"publisher","DOI":"10.3389\/fnetp.2024.1315316"},{"key":"e_1_3_3_85_2","doi-asserted-by":"publisher","DOI":"10.3389\/fnetp.2024.1379892"},{"key":"e_1_3_3_86_2","doi-asserted-by":"publisher","DOI":"10.1096\/fj.201701031R"},{"key":"e_1_3_3_87_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0101477"},{"key":"e_1_3_3_88_2","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2017.00300"},{"key":"e_1_3_3_89_2","doi-asserted-by":"publisher","DOI":"10.1186\/1756-0500-7-726"},{"key":"e_1_3_3_90_2","doi-asserted-by":"publisher","DOI":"10.1113\/JP278829"}],"container-title":["Journal of Cerebral Blood Flow &amp; Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0271678X261447119","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0271678X261447119","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0271678X261447119","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T07:47:43Z","timestamp":1789285663000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0271678X261447119"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,4]]},"references-count":89,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1177\/0271678X261447119"],"URL":"https:\/\/doi.org\/10.1177\/0271678x261447119","relation":{},"ISSN":["0271-678X","1559-7016"],"issn-type":[{"value":"0271-678X","type":"print"},{"value":"1559-7016","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,4]]}}}