{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T09:39:33Z","timestamp":1792661973190,"version":"4.5.0"},"reference-count":0,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T00:00:00Z","timestamp":1792454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Cereb Blood Flow Metab"],"abstract":"<jats:p>Vemuganti and colleagues highlight intermittent fasting (IF)'s neuroprotective potential post-stroke via autophagy and mitochondrial biogenesis. However, clinical translation faces hurdles in metabolically vulnerable patients. This letter critiques IF's bedside applicability, emphasizing post-stroke catabolic stress, dysphagia (~50% cases), sarcopenia risk, and cardiovascular concerns. Recent evidence links short eating windows to higher mortality, countering IF benefits. The obesity paradox suggests nutritional reserves aid survival. Strategies: protein-prioritized planning, dysphagia screening, dietitian monitoring, and supplements. Until RCTs confirm safety\/efficacy, prioritize nutritional adequacy. Preclinical insights warrant study.Keywords: dysphagia, intermittent fasting, neuroprotection, obesity paradox, sarcopenia<\/jats:p>","DOI":"10.1177\/0271678x261501655","type":"journal-article","created":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T04:09:51Z","timestamp":1792555791000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["EXPRESS: Letter to the Editor Regarding \u201cMuch ado about eating: Intermittent fasting and post-stroke neuroprotection\u201d"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2983-9304","authenticated-orcid":false,"given":"Guilherme Bezerra","family":"Carneiro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina Moreno","family":"Pace","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eberval Gadelha","family":"Figueiredo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,10,20]]},"container-title":["Journal of Cerebral Blood Flow &amp; Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0271678X261501655","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0271678X261501655","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T08:46:40Z","timestamp":1792658800000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0271678X261501655"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,20]]},"references-count":0,"alternative-id":["10.1177\/0271678X261501655"],"URL":"https:\/\/doi.org\/10.1177\/0271678x261501655","relation":{},"ISSN":["0271-678X","1559-7016"],"issn-type":[{"value":"0271-678X","type":"print"},{"value":"1559-7016","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,20]]},"article-number":"0271678X261501655"}}