{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T17:50:56Z","timestamp":1777917056652,"version":"3.51.4"},"reference-count":43,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2025,8,3]],"date-time":"2025-08-03T00:00:00Z","timestamp":1754179200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,8,3]],"date-time":"2025-08-03T00:00:00Z","timestamp":1754179200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100001826","name":"ZonMw","doi-asserted-by":"publisher","award":["10390012110032"],"award-info":[{"award-number":["10390012110032"]}],"id":[{"id":"10.13039\/501100001826","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Med Decis Making"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Recent studies show that low-risk pancreatic cysts may require less frequent monitoring. Future guidelines will likely adapt their recommendations accordingly. Our goal was to explore the willingness of individuals with a low-risk pancreatic cyst to undergo less frequent surveillance and to identify associated characteristics with such willingness.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This is a side study of the international PACYFIC study, which prospectively collects data on cyst surveillance, including questionnaires to assess participants\u2019 attitude toward surveillance. Individuals with low-risk cysts at baseline, without given standardized information by the study protocol, were enrolled. Their responses to the baseline question, \u201cWould you prefer less frequent surveillance? Yes\/No,\u201d were correlated with baseline characteristics using multivariable logistic regression, namely, age, country of residence, symptoms, medical and family history, time since first cyst detection, and Hospital Anxiety Depression Scale score.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of the 215 participants included from the Netherlands (\n                      <jats:italic>n<\/jats:italic>\n                      = 185) and Italy (\n                      <jats:italic>n<\/jats:italic>\n                      = 30), only 47 (22%) were willing to undergo less surveillance. Characteristics positively associated with this willingness were older age (odds ratio [OR] 1.87\u2009per 10\u2009y, 95% confidence interval [CI]: 1.15\u20133.04) and Italian residency (OR 16.35, 95% CI: 5.65\u201347.31). A medical history of cancer was negatively associated (OR 0.28, 95% CI: 0.09\u20130.90). No other associations were observed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Most participants appear unwilling to undergo less frequent cyst surveillance. Older age and residing in Italy were associated with a greater willingness toward less rigorous surveillance, while a history of cancer did the opposite. Identifying which individuals are hesitant to undergo less frequent surveillance may help clinicians tailor their counseling and can support implementation of future guideline with fewer surveillance recommendations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                    <jats:list list-type=\"bullet\">\n                      <jats:list-item>\n                        <jats:p>Most low-risk individuals were reluctant toward less frequent pancreatic cyst surveillance.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>Older age and residency in Italy were associated with a higher willingness.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>A medical history of cancer was associated with an unwillingness.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>Standardized patient information may increase the willingness, but such information has yet to be developed.<\/jats:p>\n                      <\/jats:list-item>\n                    <\/jats:list>\n                  <\/jats:sec>","DOI":"10.1177\/0272989x251352750","type":"journal-article","created":{"date-parts":[[2025,8,3]],"date-time":"2025-08-03T11:25:17Z","timestamp":1754220317000},"page":"904-912","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Patients\u2019 Attitude toward Less Frequent Surveillance of Low-Risk Pancreatic Cysts: A Multicenter European Cohort Study"],"prefix":"10.1177","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-3002-9552","authenticated-orcid":false,"given":"Marloes L. J. A.","family":"Sprij","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, The Netherlands"},{"name":"Department of Public Health, Erasmus University Medical Center, Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9419-0452","authenticated-orcid":false,"given":"Inge M. C. M.","family":"de Kok","sequence":"additional","affiliation":[{"name":"Department of Public Health, Erasmus University Medical Center, Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daan D.","family":"Nieboer","sequence":"additional","affiliation":[{"name":"Department of Public Health, Erasmus University Medical Center, Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriele","family":"Capurso","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Vita Salute San Raffaele University, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jihane","family":"Meziani","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mattheus C. B.","family":"Wielenga","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology &amp; Hepatology, Amsterdam UMC, Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mirjam C. M.","family":"van der Ende","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Catharina Hospital, Eindhoven, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marianne E.","family":"Smits","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology &amp; Hepatology, Tergooi, Hilversum, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riccardo","family":"Casadei","sequence":"additional","affiliation":[{"name":"Department of Surgery, Bologna University, Bologna, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthijs P.","family":"Schwartz","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology &amp; Hepatology, Meander Medical Center, Amersfoort, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frederike G. I.","family":"van Vilsteren","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology &amp; Hepatology, University Medical Center Groningen, Groningen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chantal","family":"Hoge","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology &amp; Hepatology, Maastricht University Medical Center, Maastricht, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rutger","family":"Quispel","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology &amp; Hepatology, Reinier de Graaf hospital, Delft, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pieter","family":"Honkoop","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology &amp; Hepatology, Albert Schweitzer Hospital, Dordrecht, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurens A.","family":"van der Waaij","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology &amp; Hepatology, Martini Hospital, Groningen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gemma","family":"Rossi","sequence":"additional","affiliation":[{"name":"Pancreato-Biliary Endoscopy and Endosonography Division, Pancreas Translational and Clinical Research Center, San Raffaele Scientific Institute IRCCS, Vita Salute San Raffaele University, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adriaan C. 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