{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T19:08:21Z","timestamp":1774552101089,"version":"3.50.1"},"reference-count":38,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2009,6,8]],"date-time":"2009-06-08T00:00:00Z","timestamp":1244419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The International Journal of Robotics Research"],"published-print":{"date-parts":[[2009,9]]},"abstract":"<jats:p> Medical nanorobotics exploits nanometer-scale components and phenomena with robotics to provide new medical diagnostic and interventional tools. Here, the architecture and main specifications of a novel medical interventional platform based on nanorobotics and nanomedicine, and suited to target regions inaccessible to catheterization, are described. The robotic platform uses magnetic resonance imaging (MRI) for feeding back information to a controller responsible for the real-time control and navigation along pre-planned paths in the blood vessels of untethered magnetic carriers, nanorobots, and\/or magnetotactic bacteria (MTB) loaded with sensory or therapeutic agents acting like a wireless robotic arm, manipulator, or other extensions necessary to perform specific remote tasks. Unlike known magnetic targeting methods, the present platform allows us to reach locations deep in the human body while enhancing targeting efficacy using real-time navigational or trajectory control. We describe several versions of the platform upgraded through additional software and hardware modules allowing enhanced targeting efficacy and operations in very difficult locations such as tumoral lesions only accessible through complex microvasculature networks. <\/jats:p>","DOI":"10.1177\/0278364908104855","type":"journal-article","created":{"date-parts":[[2009,6,9]],"date-time":"2009-06-09T00:56:07Z","timestamp":1244508967000},"page":"1169-1182","source":"Crossref","is-referenced-by-count":237,"title":["MRI-based Medical Nanorobotic Platform for the Control of Magnetic                 Nanoparticles and Flagellated Bacteria for Target Interventions in Human Capillaries"],"prefix":"10.1177","volume":"28","author":[{"given":"Sylvain","family":"Martel","sequence":"first","affiliation":[{"name":"NanoRobotics Laboratory, Department of Computer and Software Engineering,                         Institute of Biomedical Engineering, \u00c9cole Polytechnique de Montr\u00e9al (EPM),                         Campus of the Universit\u00e9 de Montr\u00e9al, P.O. Box 6079, Station Centre-ville,                         Montr\u00e9al, Qu\u00e9bec, Canada H3C 3A7,"}]},{"given":"Ouajdi","family":"Felfoul","sequence":"additional","affiliation":[{"name":"NanoRobotics Laboratory, Department of Computer and Software Engineering,                         Institute of Biomedical Engineering, \u00c9cole Polytechnique de Montr\u00e9al (EPM),                         Campus of the Universit\u00e9 de Montr\u00e9al, P.O. Box 6079, Station Centre-ville,                         Montr\u00e9al, Qu\u00e9bec, Canada H3C 3A7"}]},{"given":"Jean-Baptiste","family":"Mathieu","sequence":"additional","affiliation":[{"name":"NanoRobotics Laboratory, Department of Computer and Software Engineering,                         Institute of Biomedical Engineering, \u00c9cole Polytechnique de Montr\u00e9al (EPM),                         Campus of the Universit\u00e9 de Montr\u00e9al, P.O. Box 6079, Station Centre-ville,                         Montr\u00e9al, Qu\u00e9bec, Canada H3C 3A7"}]},{"given":"Arnaud","family":"Chanu","sequence":"additional","affiliation":[{"name":"NanoRobotics Laboratory, Department of Computer and Software Engineering,                         Institute of Biomedical Engineering, \u00c9cole Polytechnique de Montr\u00e9al (EPM),                         Campus of the Universit\u00e9 de Montr\u00e9al, P.O. Box 6079, Station Centre-ville,                         Montr\u00e9al, Qu\u00e9bec, Canada H3C 3A7"}]},{"given":"Samer","family":"Tamaz","sequence":"additional","affiliation":[{"name":"NanoRobotics Laboratory, Department of Computer and Software Engineering,                         Institute of Biomedical Engineering, \u00c9cole Polytechnique de Montr\u00e9al (EPM),                         Campus of the Universit\u00e9 de Montr\u00e9al, P.O. Box 6079, Station Centre-ville,                         Montr\u00e9al, Qu\u00e9bec, Canada H3C 3A7"}]},{"given":"Mahmood","family":"Mohammadi","sequence":"additional","affiliation":[{"name":"NanoRobotics Laboratory, Department of Computer and Software Engineering,                         Institute of Biomedical Engineering, \u00c9cole Polytechnique de Montr\u00e9al (EPM),                         Campus of the Universit\u00e9 de Montr\u00e9al, P.O. Box 6079, Station Centre-ville,                         Montr\u00e9al, Qu\u00e9bec, Canada H3C 3A7"}]},{"given":"Martin","family":"Mankiewicz","sequence":"additional","affiliation":[{"name":"NanoRobotics Laboratory, Department of Computer and Software Engineering,                         Institute of Biomedical Engineering, \u00c9cole Polytechnique de Montr\u00e9al (EPM),                         Campus of the Universit\u00e9 de Montr\u00e9al, P.O. Box 6079, Station Centre-ville,                         Montr\u00e9al, Qu\u00e9bec, Canada H3C 3A7"}]},{"given":"Nasr","family":"Tabatabaei","sequence":"additional","affiliation":[{"name":"NanoRobotics Laboratory, Department of Computer and Software Engineering,                         Institute of Biomedical Engineering, \u00c9cole Polytechnique de Montr\u00e9al (EPM),                         Campus of the Universit\u00e9 de Montr\u00e9al, P.O. Box 6079, Station Centre-ville,                         Montr\u00e9al, Qu\u00e9bec, Canada H3C 3A7"}]}],"member":"179","published-online":{"date-parts":[[2009,6,8]]},"reference":[{"key":"atypb1","first-page":"6641","volume":"60","author":"Alexiou, C.","year":"2000","journal-title":"Cancer Research"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmmm.2005.02.036"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1109\/TASC.2005.864457"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1063\/1.2431454"},{"key":"atypb5","volume-title":"IEEE International Conference on Robotics and Automation (ICRA)","author":"Bell, D.J."},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.203.3.9169677"},{"key":"atypb7","volume-title":"Proceedings of the 5th International Workshop on Microfactories (IWMF)","author":"Bey-Oueslati, R."},{"key":"atypb8","volume-title":"Blood Flow and Microcirculation","author":"Charm, S.E.","year":"1974"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.21638"},{"key":"atypb10","unstructured":"Driscoll et al. 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