{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T22:47:20Z","timestamp":1777502840048,"version":"3.51.4"},"reference-count":36,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2016,7,20]],"date-time":"2016-07-20T00:00:00Z","timestamp":1468972800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Acta Radiol"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      For pituitary tumors, positron emission tomography (PET) with\n                      <jats:sup>11<\/jats:sup>\n                      C-methonine (MET) has been reported as feasible to facilitate diagnosis. MET is well-known to accumulate in the normal pituitary glands, but almost no studies have examined the degree of MET accumulation in the normal pituitary gland.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To investigate accumulation of MET in normal pituitary gland on PET\/CT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>Among patients who underwent PET\/CT using MET over the past 7 years, 77 patients who fulfilled our criteria for normal pituitary glands were retrospectively selected. Maximum standardized uptake value (SUVmax) for the pituitary gland was measured.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>SUVmax of MET in the pituitary gland was in the range of 0.9\u20136.6 (mean\u2009\u00b1\u2009standard deviation\u2009=\u20092.60\u2009\u00b1\u20091.04). A negative correlation between SUVmax and patient age (y\u2009=\u2009\u22120.032\u2009\u00d7\u2009+\u20094.29, n\u2009=\u200977, r\u2009=\u20090.55) was found by linear regression analysis. SUVmax of the pituitary gland did not differ significantly between women and men.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>MET shows strong accumulation in normal pituitary gland. PET\/CT would thus be feasible to differentiate between normal and abnormal pituitary glands.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0284185116651005","type":"journal-article","created":{"date-parts":[[2016,6,6]],"date-time":"2016-06-06T22:44:11Z","timestamp":1465253051000},"page":"362-366","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":14,"title":["Accumulation of\n                    <sup>11<\/sup>\n                    C-methionine in the normal pituitary gland on\n                    <sup>11<\/sup>\n                    C-methionine PET"],"prefix":"10.1177","volume":"58","author":[{"given":"Noriaki","family":"Tomura","sequence":"first","affiliation":[{"name":"Department of Neuroradiology, Southern Tohoku Research Institute for Neuroscience, Southern Tohoku General Hospital, Koriyama, Fukushima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshiyuiki","family":"Saginoya","sequence":"additional","affiliation":[{"name":"Department of Radiology, Southern Tohoku Research Institute for Neuroscience, Southern Tohoku General Hospital, Koriyama, Fukushima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuaki","family":"Mizuno","sequence":"additional","affiliation":[{"name":"Department of Radiology, Southern Tohoku Research Institute for Neuroscience, Southern Tohoku General Hospital, Koriyama, Fukushima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiromi","family":"Goto","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Southern Tohoku Research Institute for Neuroscience, Southern Tohoku General Hospital, Koriyama, Fukushima, 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