{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T22:50:16Z","timestamp":1777503016887,"version":"3.51.4"},"reference-count":28,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2016,12,19]],"date-time":"2016-12-19T00:00:00Z","timestamp":1482105600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Acta Radiol"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Inadequate neointimal coverage of stent struts is associated with late stent thrombosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To demonstrate the extent of neointimal coverage and strut malapposition in titanium-nitride-oxide-coated bioactive stents (BAS) versus everolimus-eluting stents (EES) by optical coherence tomography (OCT) performed at 18-month follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>In the BASE-ACS trial, 827 patients presenting with acute coronary syndrome were randomized to receive either BAS or EES. Forty patients (20 BAS, 20 EES) underwent OCT at 18-month follow-up for evaluation of stent strut coverage, malapposition, and neointimal hyperplasia (NIH). Primary endpoint was binary stent strut coverage (ratio of covered struts to all analyzed struts multiplied by 100). Co-primary endpoint was the percentage of malapposed struts.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We analyzed 3465 struts in 330 cross-sections of BAS and 3327 struts in 316 cross-sections of EES. Binary stent strut coverage, based on strut-level analysis, was higher with BAS versus EES (99.5% versus 94.2%, respectively; P\u2009&lt;\u20090.001), the strut-level percentage of malapposed struts was lower with BAS (0.6% versus 2.5%, respectively; P\u2009&lt;\u20090.001). Yet, the mean NIH thickness was greater with BAS (237\u2009\u00b1\u2009125 versus 108\u2009\u00b1\u200962\u2009\u00b5m, respectively; P\u2009&lt;\u20090.001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In the current post-hoc analysis with OCT performed at 18 months, binary strut coverage, based on strut-level analysis, was higher with BAS versus EES; strut-level malapposed struts were fewer with BAS; yet, BAS induced thicker NIH.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0284185116683573","type":"journal-article","created":{"date-parts":[[2017,3,6]],"date-time":"2017-03-06T17:58:43Z","timestamp":1488823123000},"page":"1077-1084","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Optical coherence tomography follow-up 18 months after titanium-nitride-oxide-coated versus everolimus-eluting stent implantation in patients with acute coronary syndrome"],"prefix":"10.1177","volume":"58","author":[{"given":"Pasi","family":"Karjalainen","sequence":"first","affiliation":[{"name":"Heart Center, Satakunta Central Hospital, Pori, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tuomas","family":"Paana","sequence":"additional","affiliation":[{"name":"Heart Center, Satakunta Central Hospital, Pori, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antti","family":"Ylitalo","sequence":"additional","affiliation":[{"name":"Heart Center, Satakunta Central Hospital, Pori, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jussi","family":"Sia","sequence":"additional","affiliation":[{"name":"Heart Center, Kokkola Central Hospital, Kokkola, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wail","family":"Nammas","sequence":"additional","affiliation":[{"name":"Heart Center, 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