{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T18:15:42Z","timestamp":1785176142646,"version":"3.55.0"},"reference-count":24,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2017,1,16]],"date-time":"2017-01-16T00:00:00Z","timestamp":1484524800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Acta Radiol"],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Otosclerotic foci are usually seen as minute low-density lesions and this may be attributed to relatively low sensitivity on visual assessment using computed tomography (CT). Otosclerotic foci can be detected by using the accurate region of interest (ROI) setting, while small ROI settings by less-experienced radiologists may result in false negative findings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate the diagnostic ability of our proposed method (\u201cotosclerosis-weighted\u201d imaging [OWI]), which is based on reversing the density, compared with conventional CT (CCT) imaging alone.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>Temporal bone CTs of consecutive patients with otosclerosis were analyzed. Gender- and age-matched control participants were also included. All CT images were obtained using a 64-detector row scanner. OWI was obtained by extracting the temporal bone region using the threshold technique and reversing the density (black to white). Four independent radiologists took part in two reading sessions. In the first session, the observers read only CCT imaging. In the second session, they read OWI along with the CCT imaging. Sensitivity was assessed for the four readers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Thirty temporal bones of 25 patients with otosclerosis (3 men, 22 women; mean age, 53.9\u2009\u00b1\u20099.0 years) and 30 temporal bones of 30 control participants (4 men, 26 women; mean age, 44.0\u2009\u00b1\u200916.2 years) were included. For all observers, reading with a combination of the two methods was associated with a higher sensitivity (63.3\u201380.0%) than with conventional CT images alone (30.0\u201360.0%; P\u2009&lt;\u20090.05, each).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Application of our proposed method based on threshold value may help detect foci of fenestral otosclerosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0284185116687172","type":"journal-article","created":{"date-parts":[[2017,1,18]],"date-time":"2017-01-18T04:22:10Z","timestamp":1484713330000},"page":"1215-1221","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Additive value of \u201cotosclerosis-weighted\u201d images for the CT diagnosis of fenestral otosclerosis"],"prefix":"10.1177","volume":"58","author":[{"given":"Koji","family":"Yamashita","sequence":"first","affiliation":[{"name":"Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akio","family":"Hiwatashi","sequence":"additional","affiliation":[{"name":"Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osamu","family":"Togao","sequence":"additional","affiliation":[{"name":"Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masatoshi","family":"Kondo","sequence":"additional","affiliation":[{"name":"Department of Medical Technology, Kyushu University Hospital, Fukuoka, 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