{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T04:06:02Z","timestamp":1790049962947,"version":"4.0.1"},"reference-count":35,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2017,3,17]],"date-time":"2017-03-17T00:00:00Z","timestamp":1489708800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Acta Radiol"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Microcephaly is one of the most common fetal structural abnormalities, and prenatal microcephaly is considered a group I malformation of cortical development diagnosed according to ultrasound (US) skull measurements.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate the agreement between fetal head US and magnetic resonance imaging (MRI) biometric measurements of suspected microcephalic fetuses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>This institutional review board-approved retrospective study with waived informed consent included 180 pregnant women and was conducted at our medical center from March 2011 to April 2013. Biparietal diameter (BPD) and occipitofrontal diameter (OFD) results of fetal head US normograms were compared to normograms for MRI. We used Pearson and Spearman rho non-parametric correlation coefficients to assess the association between two quantitative variables, paired t-test for paired quantitative variables, and McNemar test for paired qualitative variables.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The average BPD but not the average OFD percentiles in fetal head US differed significantly from the MRI results ( P\u2009&lt;\u20090.0001). When looking at the accepted microcephaly threshold, both BPD and OFD percentiles differed significantly from MRI ( P\u2009&lt;\u20090.0001 and P\u2009&lt;\u20090.004, respectively). There was no correlation between US-measured skull biometry and MRI-measured brain biometry. Estimated cerebrospinal fluid volumes were significantly lower in the study group compared to 120 fetuses with normal findings in prenatal head US and MRI. Also, we have created a MRI-based normogram of fetal head circumference and gestational age.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The diagnosis of microcephaly by US alone may be insufficient and ideally should be validated by MRI before a final diagnosis is established.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0284185117698865","type":"journal-article","created":{"date-parts":[[2017,3,17]],"date-time":"2017-03-17T08:49:10Z","timestamp":1489740550000},"page":"1519-1527","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":15,"title":["Discrepancy in fetal head biometry between ultrasound and MRI in suspected microcephalic fetuses"],"prefix":"10.1177","volume":"58","author":[{"given":"Gal","family":"Yaniv","sequence":"first","affiliation":[{"name":"Department of Diagnostic Imaging, Sheba Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eldad","family":"Katorza","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Sheba Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vered","family":"Tsehmaister Abitbol","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Imaging, Sheba Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arik","family":"Eisenkraft","sequence":"additional","affiliation":[{"name":"The Institute for Research in Military Medicine, The Faculty of Medicine, The Hebrew University of Jerusalem, Israel"},{"name":"The IDF Medical Corps"},{"name":"Department of Pediatrics, Safra Children\u2019s Hospital, Sheba Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronen","family":"Bercovitz","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Imaging, Sheba Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salim","family":"Bader","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Imaging, Sheba Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Hoffmann","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Imaging, Sheba Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2017,3,17]]},"reference":[{"key":"bibr1-0284185117698865","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/aws019"},{"key":"bibr2-0284185117698865","doi-asserted-by":"publisher","DOI":"10.1002\/jcu.1870080104"},{"key":"bibr3-0284185117698865","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(84)90027-9"},{"key":"bibr4-0284185117698865","first-page":"908","volume":"69","author":"Chervenak FA","year":"1987","journal-title":"Obstet Gynecol"},{"key":"bibr5-0284185117698865","doi-asserted-by":"publisher","DOI":"10.1177\/0883073808321045"},{"key":"bibr6-0284185117698865","doi-asserted-by":"publisher","DOI":"10.1002\/uog.7556"},{"key":"bibr7-0284185117698865","doi-asserted-by":"publisher","DOI":"10.1002\/uog.7760"},{"key":"bibr8-0284185117698865","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181b783f7"},{"key":"bibr9-0284185117698865","doi-asserted-by":"publisher","DOI":"10.1542\/pir.17-11-386"},{"key":"bibr10-0284185117698865","doi-asserted-by":"publisher","DOI":"10.1016\/j.conb.2004.01.003"},{"key":"bibr11-0284185117698865","doi-asserted-by":"publisher","DOI":"10.1016\/j.yapd.2005.04.003"},{"key":"bibr12-0284185117698865","doi-asserted-by":"publisher","DOI":"10.1002\/uog.5192"},{"key":"bibr13-0284185117698865","doi-asserted-by":"publisher","DOI":"10.1002\/uog.966"},{"key":"bibr14-0284185117698865","doi-asserted-by":"publisher","DOI":"10.1002\/uog.1901"},{"key":"bibr15-0284185117698865","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2005.10.004"},{"key":"bibr16-0284185117698865","doi-asserted-by":"publisher","DOI":"10.1002\/uog.5225"},{"key":"bibr17-0284185117698865","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.181.1.1887021"},{"key":"bibr18-0284185117698865","first-page":"1671","volume":"15","author":"Fogliarini C","year":"2005","journal-title":"Part I: Normal cortical maturation. 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