{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T19:00:45Z","timestamp":1784228445844,"version":"3.55.0"},"reference-count":14,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2017,5,10]],"date-time":"2017-05-10T00:00:00Z","timestamp":1494374400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Acta Radiol"],"published-print":{"date-parts":[[2018,2]]},"abstract":"\n Background<\/jats:title>\n The BI-RADS provides descriptors for microcalcifications based on morphology and distribution. However, the descriptor for category 4A microcalcifications is not specified in the 5th BI-RADS nor in the prior editions.<\/jats:p>\n <\/jats:sec>\n \n Purpose<\/jats:title>\n To investigate how the category 4A assessment is applied to suspicious microcalcifications, and the appropriate descriptors for category 4A assessment for microcalcifications seen on mammography.<\/jats:p>\n <\/jats:sec>\n \n Material and Methods<\/jats:title>\n From June 2008 to November 2011, 296 women with 305 suspicious microcalcifications that were assessed as BI-RADS category 4A, who underwent imaging-guided biopsy or surgery, were included. Mammograms were reviewed and imaging features were analyzed according to the morphology and distribution descriptors of the 5th edition of BI-RADS. Pathological results were considered as the reference standard. Positive predictive values were calculated and compared between morphology and distribution descriptors.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n The overall positive predictive value (PPV) of category 4A microcalcifications was 17.7% (54\/305). Most common descriptors for category 4A microcalcifications were amorphous morphology (73.1%) and grouped distribution (71.1%). PPVs of individual morphology descriptors were as follows: amorphous\u2009=\u20097.2%; coarse heterogeneous\u2009=\u200912.8%; fine pleomorphic or fine linear\/fine linear branching\u2009=\u200991.4% ( P\u2009<\u20090.001). PPVs of distribution descriptors were as follows: regional\u2009=\u200913.2%; grouped\u2009=\u200916.1%; linear\/segmental\u2009=\u200954.5% ( P\u2009<\u20090.001). For morphology and distribution descriptors combinations, PPVs for amorphous\/regional and amorphous\/grouped microcalcifications were 6.8% and 6.9%, while PPVs of other combinations were higher than 10%, respectively.<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Common descriptors used in category 4A assessment for microcalcifications are amorphous morphology and grouped distribution. PPV of amorphous\/regional and amorphous\/grouped microcalcifications were suitable for category 4A assessment.<\/jats:p>\n <\/jats:sec>","DOI":"10.1177\/0284185117709036","type":"journal-article","created":{"date-parts":[[2017,5,11]],"date-time":"2017-05-11T11:17:22Z","timestamp":1494501442000},"page":"147-153","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["\u201cCategory 4A\u201d microcalcifications: how should this subcategory be applied to microcalcifications seen on mammography?"],"prefix":"10.1177","volume":"59","author":[{"given":"Jihee","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Radiology, Severance Hospital, Research Institute of Radiological Science, Yonsei University, College of Medicine, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun-Kyung","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Radiology, Severance Hospital, Research Institute of Radiological Science, Yonsei University, College of Medicine, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min Jung","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Radiology, Severance Hospital, Research Institute of Radiological Science, Yonsei University, College of Medicine, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hee Jung","family":"Moon","sequence":"additional","affiliation":[{"name":"Department of Radiology, Severance Hospital, Research Institute of Radiological Science, Yonsei University, College of Medicine, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jung Hyun","family":"Yoon","sequence":"additional","affiliation":[{"name":"Department of Radiology, Severance Hospital, Research Institute of Radiological Science, Yonsei University, College of Medicine, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2017,5,10]]},"reference":[{"key":"bibr1-0284185117709036","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-200202000-00013"},{"key":"bibr2-0284185117709036","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-007-9395-7"},{"key":"bibr3-0284185117709036","volume-title":"Breast Imaging Reporting AndData System","author":"American College of Radiology","year":"2013","edition":"5"},{"key":"bibr4-0284185117709036","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.171.1.9648759"},{"key":"bibr5-0284185117709036","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-004-2593-9"},{"key":"bibr6-0284185117709036","volume-title":"Breast Imaging ReportingAnd Data System","author":"American College of Radiology","year":"2003","edition":"4"},{"key":"bibr7-0284185117709036","doi-asserted-by":"publisher","DOI":"10.1016\/j.rx.2011.04.004"},{"key":"bibr8-0284185117709036","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.09.3423"},{"key":"bibr9-0284185117709036","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-014-4362-6"},{"key":"bibr10-0284185117709036","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.174.6.1741769"},{"key":"bibr11-0284185117709036","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2422052130"},{"key":"bibr12-0284185117709036","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2212010164"},{"key":"bibr13-0284185117709036","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-011-2167-4"},{"key":"bibr14-0284185117709036","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.08.1127"}],"container-title":["Acta Radiologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0284185117709036","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0284185117709036","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0284185117709036","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:20:47Z","timestamp":1777389647000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0284185117709036"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5,10]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["10.1177\/0284185117709036"],"URL":"https:\/\/doi.org\/10.1177\/0284185117709036","relation":{},"ISSN":["0284-1851","1600-0455"],"issn-type":[{"value":"0284-1851","type":"print"},{"value":"1600-0455","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,5,10]]}}}