{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T09:10:19Z","timestamp":1783242619088,"version":"3.54.6"},"reference-count":30,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2017,7,10]],"date-time":"2017-07-10T00:00:00Z","timestamp":1499644800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Acta Radiol"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Ribbing disease, or multiple diaphyseal sclerosis, is a rare benign bone dysplasia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To systematically review the literature to determine the clinical and radiological presentation of patients with Ribbing disease as well as the effects of attempted treatments.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>We considered individual patient data of patients diagnosed with Ribbing disease derived from patient reports and patient series. All stages of the review were performed by two reviewers independently. Standard descriptive statistics were used for quantitative analyses and mixed model analyses were used when appropriate<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The literature search yielded 420 unique hits of which 23 studies were included, covering a total of 40 patients of whom 29 had bilateral involvement. The mean age at diagnosis was 35 years and the mean time between diagnosis and onset of symptoms, mostly pain, was five years (range\u2009=\u20091\u201316 years). The tibial diaphysis was the most commonly involved bone in 35 of 36 patients. Non-surgical treatment consisted of non-steroidal anti-inflammatory drugs (NSAIDs), prednisone, and bisphophonates with mixed results. Surgical treatment consisted of intramedullary reaming and fenestration and was very effective to reduce pain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The clinical presentation and imaging findings of patients with Ribbing disease are becoming more apparent. However, there is paucity of evidence on the natural disease progression and effectiveness of treatment modalities.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0284185117719575","type":"journal-article","created":{"date-parts":[[2017,10,26]],"date-time":"2017-10-26T10:16:04Z","timestamp":1509012964000},"page":"448-453","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":13,"title":["Ribbing disease: a systematic review"],"prefix":"10.1177","volume":"59","author":[{"given":"Bart G","family":"Pijls","sequence":"first","affiliation":[{"name":"Department of Orthopaedics, Leiden University Medical Center, Leiden, The Netherlands"},{"name":"Department of Orthopaedics, Haga Hospital The Hague, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koen","family":"Steentjes","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Haga Hospital The Hague, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan W","family":"Schoones","sequence":"additional","affiliation":[{"name":"Walaeus Library, Leiden University Medical Centre, Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sander PD","family":"Dijkstra","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Leiden University Medical Center, Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2017,7,10]]},"reference":[{"key":"bibr1-0284185117719575","doi-asserted-by":"publisher","DOI":"10.3109\/00016924909138232"},{"key":"bibr2-0284185117719575","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-200211000-00022"},{"key":"bibr3-0284185117719575","doi-asserted-by":"publisher","DOI":"10.3944\/AOTT.2011.2421"},{"key":"bibr4-0284185117719575","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2013.01.007"},{"key":"bibr5-0284185117719575","doi-asserted-by":"publisher","DOI":"10.1007\/s003300000495"},{"key":"bibr6-0284185117719575","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.b2700"},{"key":"bibr7-0284185117719575","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.c2627"},{"key":"bibr8-0284185117719575","doi-asserted-by":"crossref","unstructured":"Petrie A. 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