{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T22:54:27Z","timestamp":1777503267893,"version":"3.51.4"},"reference-count":22,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2017,8,9]],"date-time":"2017-08-09T00:00:00Z","timestamp":1502236800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Acta Radiol"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Portosystemic shunt obliteration by surgical or interventional radiological techniques can be effective for patients with hepatic encephalopathy (HE) although this approach is often associated with accumulation of ascites and\/or formation of esophageal varices.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate the clinical efficacy and safety of shunt-preserving disconnection of the portosystemic circulation (SPDPS) in patients with HE.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>Nine patients with HE and a splenorenal shunt were treated by SPDPS: eight underwent selective coil embolization of the splenic vein and one underwent stent-graft closure of the shunt. The primary endpoint was change in HE severity based on the West-Haven criteria. The secondary endpoints were changes in serum ammonia levels, hepatic function, HE recurrence during the follow-up period, and post-treatment HE recurrence based on the West\u2013Haven diagnostic criteria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The technical success rate was 100% with no severe complications. After the procedure, the mean portal blood pressure increased from 18\u2009mmHg to 22\u2009mmHg ( P\u2009=\u20090.02), the mean HE grades fell from 2.1 to 1.1 ( P\u2009&lt;\u20090.01), and one month after the procedure, the mean serum ammonia level decreased from 177\u2009\u00b5g\/dL to 87\u2009\u00b5g\/dL ( P\u2009=\u20090.03) and the mean total Child-Pugh score from 8 to 7 ( P\u2009=\u20090.07).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>SPDPS using selective coil embolization and stent-graft closure of the shunt can be an effective and safe treatment for patients with HE.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0284185117722810","type":"journal-article","created":{"date-parts":[[2017,8,9]],"date-time":"2017-08-09T08:23:10Z","timestamp":1502266990000},"page":"441-447","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Shunt-preserving disconnection of the portal to systemic circulation in patients with hepatic encephalopathy"],"prefix":"10.1177","volume":"59","author":[{"given":"Osamu","family":"Ikeda","sequence":"first","affiliation":[{"name":"Department of Diagnostic Radiology, Graduate School of Life Sciences, Kumamoto University, Kumamoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seijiro","family":"Inoue","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, Graduate School of Life Sciences, Kumamoto University, Kumamoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshitaka","family":"Tamura","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, Graduate School of Life Sciences, Kumamoto University, Kumamoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yo-ichi","family":"Yamashita","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Graduate School of Life Sciences, Kumamoto University, Kumamoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideo","family":"Baba","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Graduate School of Life Sciences, Kumamoto University, Kumamoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukihiro","family":"Inomata","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery and Transplantation, Graduate School of Life Sciences, Kumamoto University, Kumamoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuyuki","family":"Yamashita","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, Graduate School of Life Sciences, Kumamoto University, Kumamoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,8,9]]},"reference":[{"key":"bibr1-0284185117722810","doi-asserted-by":"publisher","DOI":"10.1002\/hep.27210"},{"key":"bibr2-0284185117722810","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.38048.506134.EE"},{"key":"bibr3-0284185117722810","doi-asserted-by":"publisher","DOI":"10.1007\/s11011-013-9383-5"},{"key":"bibr4-0284185117722810","doi-asserted-by":"publisher","DOI":"10.1007\/s11011-012-9372-0"},{"key":"bibr5-0284185117722810","doi-asserted-by":"publisher","DOI":"10.1002\/hep.510250609"},{"key":"bibr6-0284185117722810","first-page":"96","volume":"93","author":"Kashida H","year":"1996","journal-title":"Nihon Shokakibyo Gakkai Zasshi"},{"key":"bibr7-0284185117722810","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(81)90294-4"},{"key":"bibr8-0284185117722810","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(84)90146-X"},{"key":"bibr9-0284185117722810","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.165.3.3685350"},{"key":"bibr10-0284185117722810","doi-asserted-by":"publisher","DOI":"10.1007\/BF02806529"},{"key":"bibr11-0284185117722810","first-page":"508","volume":"90","author":"Kawanaka H","year":"1995","journal-title":"Am J Gastroenterol"},{"key":"bibr12-0284185117722810","first-page":"1026","volume":"92","author":"Akahane T","year":"1997","journal-title":"Am J Gastroenterol"},{"key":"bibr13-0284185117722810","first-page":"24","volume":"1","author":"Ikeda O","year":"2012","journal-title":"Acta Radiol Short Rep"},{"key":"bibr14-0284185117722810","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvir.2010.06.014"},{"key":"bibr15-0284185117722810","doi-asserted-by":"publisher","DOI":"10.1097\/01.RVI.0000136984.47892.4C"},{"key":"bibr16-0284185117722810","first-page":"129","volume":"20","author":"Wind P","year":"1998","journal-title":"Review of the literature. 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