{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T22:55:22Z","timestamp":1777503322528,"version":"3.51.4"},"reference-count":23,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2017,9,12]],"date-time":"2017-09-12T00:00:00Z","timestamp":1505174400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Acta Radiol"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Magnetic resonance imaging (MRI) is widely used in several muscle disorders. Diffusion-weighted imaging (DWI) is an imaging modality, which can reflect microstructural tissue composition. The apparent diffusion coefficient (ADC) is used to quantify the random motion of water molecules in tissue.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To investigate ADC values in patients with myositis and non-inflammatory myopathy and to analyze possible associations between ADC and laboratory parameters in these patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>\n                      Overall, 17 patients with several myositis entities, eight patients with non-inflammatory myopathies, and nine patients without muscle disorder as a control group were included in the study (mean age\u2009=\u200955.3\u2009\u00b1\u200914.3 years). The diagnosis was confirmed by histopathology in every case. DWI was obtained in a 1.5-T scanner using two b-values: 0 and 1000\u2009s\/mm\n                      <jats:sup>2<\/jats:sup>\n                      . In all patients, the blood sample was acquired within three days to the MRI. The following serological parameters were estimated: C-reactive protein, lactate dehydrogenase, alanine aminotransferase, aspartate aminotransferase, creatine kinase, and myoglobine.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The estimated mean ADC value for the myositis group was 1.89\u2009\u00b1\u20090.37\u2009\u00d7\u200910\n                      <jats:sup>\u20133\u2009<\/jats:sup>\n                      mm\n                      <jats:sup>2<\/jats:sup>\n                      \/s and for the non-inflammatory myopathy group was 1.79\u2009\u00b1\u20090.33\u2009\u00d7\u200910\n                      <jats:sup>\u20133<\/jats:sup>\n                      \u2009mm\n                      <jats:sup>2<\/jats:sup>\n                      \/s, respectively. The mean ADC values (1.15\u2009\u00b1\u20090.37\u2009\u00d7\u200910\n                      <jats:sup>\u20133<\/jats:sup>\n                      \u2009mm\n                      <jats:sup>2<\/jats:sup>\n                      \/s) were significantly higher to unaffected muscles (vs. myositis P\u2009=\u20090.0002 and vs. myopathy P\u2009=\u20090.0021). There were no significant correlations between serological parameters and ADC values.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Affected muscles showed statistically significantly higher ADC values than normal muscles. No linear correlations between ADC and serological parameters were identified.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0284185117731448","type":"journal-article","created":{"date-parts":[[2017,9,13]],"date-time":"2017-09-13T02:10:41Z","timestamp":1505268641000},"page":"694-699","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Apparent diffusion coefficient (ADC) does not correlate with different serological parameters in myositis and myopathy"],"prefix":"10.1177","volume":"59","author":[{"given":"Hans-Jonas","family":"Meyer","sequence":"first","affiliation":[{"name":"Department of Diagnostic Radiology, Martin-Luther University Halle-Wittenberg, Halle, Germany"},{"name":"Department of Diagnostic and Interventional Radiology, University of Leipzig, Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oliver","family":"Ziemann","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, Martin-Luther University Halle-Wittenberg, Halle, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malte","family":"Kornhuber","sequence":"additional","affiliation":[{"name":"Department of Neurology, Martin-Luther University Halle-Wittenberg, Halle, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Emmer","sequence":"additional","affiliation":[{"name":"Department of Neurology, Martin-Luther University Halle-Wittenberg, Halle, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulf","family":"Qu\u00e4schling","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, University of Leipzig, Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Schob","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, University of Leipzig, Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexey","family":"Surov","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology, University of Leipzig, Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,9,12]]},"reference":[{"key":"bibr1-0284185117731448","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1402225"},{"key":"bibr2-0284185117731448","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.179.4.1790967"},{"key":"bibr3-0284185117731448","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-016-8350-6"},{"key":"bibr4-0284185117731448","doi-asserted-by":"publisher","DOI":"10.1016\/j.rcl.2015.01.005"},{"key":"bibr5-0284185117731448","doi-asserted-by":"publisher","DOI":"10.4103\/2156-7514.81294"},{"key":"bibr6-0284185117731448","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-016-8139-7"},{"key":"bibr7-0284185117731448","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.21209"},{"key":"bibr8-0284185117731448","doi-asserted-by":"publisher","DOI":"10.1007\/s00256-015-2141-5"},{"key":"bibr9-0284185117731448","doi-asserted-by":"publisher","DOI":"10.1007\/s00256-014-1850-5"},{"key":"bibr10-0284185117731448","doi-asserted-by":"publisher","DOI":"10.1007\/s00256-010-0986-1"},{"key":"bibr11-0284185117731448","doi-asserted-by":"publisher","DOI":"10.1002\/mus.25099"},{"key":"bibr12-0284185117731448","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.10091547"},{"key":"bibr13-0284185117731448","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keh130"},{"key":"bibr14-0284185117731448","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0079008"},{"key":"bibr15-0284185117731448","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.161.2.3763909"},{"key":"bibr16-0284185117731448","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.20140261"},{"key":"bibr17-0284185117731448","doi-asserted-by":"publisher","DOI":"10.1016\/j.lpm.2011.01.005"},{"key":"bibr18-0284185117731448","doi-asserted-by":"publisher","DOI":"10.1177\/0300060513503760"},{"key":"bibr19-0284185117731448","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.20789"},{"key":"bibr20-0284185117731448","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.13.11081"},{"key":"bibr21-0284185117731448","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.21707"},{"key":"bibr22-0284185117731448","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.08.1340"},{"key":"bibr23-0284185117731448","doi-asserted-by":"crossref","unstructured":"Zeng Q, Dong F, Shi F, et\u00a0al. Apparent diffusion coefficient maps obtained from high b value diffusion-weighted imaging in the preoperative evaluation of gliomas at 3T: comparison with standard b value diffusion-weighted imaging. Eur Radiol 2017. doi: 10.1007\/s00330-017-4910-0.","DOI":"10.1007\/s00330-017-4910-0"}],"container-title":["Acta Radiologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0284185117731448","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0284185117731448","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0284185117731448","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:21:15Z","timestamp":1777389675000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0284185117731448"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9,12]]},"references-count":23,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["10.1177\/0284185117731448"],"URL":"https:\/\/doi.org\/10.1177\/0284185117731448","relation":{},"ISSN":["0284-1851","1600-0455"],"issn-type":[{"value":"0284-1851","type":"print"},{"value":"1600-0455","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,9,12]]}}}