{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T17:20:19Z","timestamp":1787678419385,"version":"build-2784847793"},"reference-count":37,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2020,1,19]],"date-time":"2020-01-19T00:00:00Z","timestamp":1579392000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Acta Radiol"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Uterine fibroid embolization (UFE) is an effective treatment for uterine leiomyomata. Optimizing the choice of embolic agents is imperative to achieve better patient outcomes with maximum resource utilization.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate the efficacy and cost-effectiveness of trisacryl gelatin microspheres (TAGM) versus combined TAGM and gelatin sponge (GS) embolization in the treatment of symptomatic uterine leiomyomata.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>Between July 2007 and December 2010, 106 consecutive patients underwent UFE with TAGM. Between January 2011 and December 2016, 123 consecutive patients underwent UFE with a combination of TAGM\/GS. The primary outcomes were successful infarction rate (\u226590% infarction) of the dominant leiomyoma and percentage reduction in uterine and dominant leiomyoma volume on MRI at six months. Secondary outcomes included adverse event rates, pain scores, and change in clinical symptoms at six months. The embolic agents utilized per procedure were recorded and a cost-effectiveness analysis was performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Baseline characteristics of both groups were similar. Successful infarction was achieved in 93.2% of the TAGM group and 94.6% of the TAGM\/GS group ( P\u2009=\u20090.52). Reduction in uterine volume (TAGM 40.7%, TAGM\/GS 44.4%, P\u2009=\u20090.16) and dominant leiomyoma volume (TAGM 47.6%, TAGM\/GS 50.1%, P\u2009=\u20090.29) at six months was similar. No significant difference was observed in symptom improvement at six months ( P\u2009=\u20090.8). The mean number of TAGM vials utilized and cost per procedure was 6.3 and $1688.40 for TAGM embolization and 3.6 and $979.50 for TAGM\/GS embolization, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Primary and secondary outcomes were comparable when performing UFE with TAGM versus combined TAGM\/GS. The combined use of TAGM\/GS reduced the mean cost of embolic agents by 42%.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0284185119898660","type":"journal-article","created":{"date-parts":[[2020,1,19]],"date-time":"2020-01-19T23:43:19Z","timestamp":1579477399000},"page":"1287-1296","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Comparison of outcomes and cost-effectiveness of trisacryl gelatin microspheres alone versus combined trisacryl gelatin microspheres and gelatin sponge embolization in uterine fibroid embolization"],"prefix":"10.1177","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5767-0908","authenticated-orcid":false,"given":"Terence P","family":"Farrell","sequence":"first","affiliation":[{"name":"Department of Radiology, St James\u2019s Hospital, Dublin, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Garvey","sequence":"additional","affiliation":[{"name":"Department of Radiology, St James\u2019s Hospital, Dublin, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niamh C","family":"Adams","sequence":"additional","affiliation":[{"name":"Department of Radiology, St James\u2019s Hospital, Dublin, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas","family":"Mulholland","sequence":"additional","affiliation":[{"name":"Department of Radiology, St James\u2019s Hospital, Dublin, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J Mark","family":"Ryan","sequence":"additional","affiliation":[{"name":"Department of Radiology, St James\u2019s Hospital, Dublin, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Guiney","sequence":"additional","affiliation":[{"name":"Department of Radiology, St James\u2019s Hospital, Dublin, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niall","family":"McEniff","sequence":"additional","affiliation":[{"name":"Department of Radiology, St James\u2019s Hospital, Dublin, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,1,19]]},"reference":[{"key":"bibr1-0284185119898660","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000296526.71749.c9"},{"key":"bibr2-0284185119898660","doi-asserted-by":"publisher","DOI":"10.1016\/S1051-0443(99)70212-5"},{"key":"bibr3-0284185119898660","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e318183fbab"},{"key":"bibr4-0284185119898660","doi-asserted-by":"publisher","DOI":"10.1055\/s-0043-106259"},{"key":"bibr5-0284185119898660","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2463070260"},{"key":"bibr6-0284185119898660","doi-asserted-by":"publisher","DOI":"10.1007\/s00270-013-0790-0"},{"key":"bibr7-0284185119898660","unstructured":"The Economist Intelligence Unit. 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