{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T23:46:24Z","timestamp":1777506384641,"version":"3.51.4"},"reference-count":31,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2020,2,16]],"date-time":"2020-02-16T00:00:00Z","timestamp":1581811200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Acta Radiol"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>It has been demonstrated that the number of metastatic axillary lymph nodes (mALNs) influence disease-free and overall survival in patients with breast cancer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To determine if the ALN size is more accurate than the ALN apparent diffusion coefficient (ADC) value to predict metastatic involvement in newly diagnosed breast cancer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>\n                      A total of 44 patients with breast cancer were included. Magnetic resonance imaging (MRI) examinations were performed on a 1.5-T system with sagittal T1-weighted fast spin-echo non-fat saturated, sagittal T2-weighted fast spin-echo non-fat saturated, axial diffusion-weighted imaging echo-planar (b values of 0 and 700\u2009s\/mm\n                      <jats:sup>2<\/jats:sup>\n                      ), and non-contrast axial VIBRANT sequences. The size and the ADC value were obtained for ALN ipsilateral and contralateral to breast cancer. The reference standard was the histopathologic lymph node status.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      mALN had a greater cortical thickness compared to contralateral non-mALN (10.3\u2009\u00b1\u20095.32\u2009mm vs. 4\u2009\u00b1\u20091.17\u2009mm, P \u2264 0.001). The threshold of \u22656.7\u2009mm for predicting axillary metastatic involvement had a sensitivity and a specificity of 80.0% and 97.7%, respectively. The ADC value of mALN was significantly higher than the contralateral non-mALN (0.90\u2009\u00b1\u20090.12\u2009\u00d7\u200910\n                      <jats:sup>\u22123<\/jats:sup>\n                      mm\n                      <jats:sup>2<\/jats:sup>\n                      \/s vs. 0.78\u2009\u00b1\u20090.12\u2009\u00d7\u200910\n                      <jats:sup>\u22123<\/jats:sup>\n                      mm\n                      <jats:sup>2<\/jats:sup>\n                      \/s; P\u2009=\u20090.001). The threshold of \u22650.86\u2009\u00d7\u200910\n                      <jats:sup>\u22123<\/jats:sup>\n                      mm\n                      <jats:sup>2<\/jats:sup>\n                      \/s had a sensitivity and a specificity of 66.7% and 76.7%, respectively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our results indicate that the cortical thickness has a better diagnostic performance in the differentiation of metastatic and non-metastatic lymph nodes than the lymph node ADC.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0284185120903449","type":"journal-article","created":{"date-parts":[[2020,2,17]],"date-time":"2020-02-17T01:57:07Z","timestamp":1581904627000},"page":"1494-1504","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Does axillary lymph node size predict better metastatic involvement than apparent diffusion coefficient (ADC) value in women with newly diagnosed breast cancer?"],"prefix":"10.1177","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7135-5656","authenticated-orcid":false,"given":"Yazm\u00edn Aseret","family":"Ram\u00edrez-Galv\u00e1n","sequence":"first","affiliation":[{"name":"Department of Radiology and Imaging, Faculty of Medicine, Hospital Universitario \u201cDr. Jos\u00e9 Eleuterio Gonz\u00e1lez,\u201d Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo Le\u00f3n, M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Servando","family":"Cardona-Huerta","sequence":"additional","affiliation":[{"name":"Breast Cancer Center, Hospital Zambrano Hellion, Tecnol\u00f3gico de Monterrey, San Pedro Garza Garc\u00eda, Nuevo Le\u00f3n, M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guillermo","family":"Elizondo-Riojas","sequence":"additional","affiliation":[{"name":"Department of Radiology and Imaging, Faculty of Medicine, Hospital Universitario \u201cDr. Jos\u00e9 Eleuterio Gonz\u00e1lez,\u201d Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo Le\u00f3n, M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neri Alejandro","family":"\u00c1lvarez-Villalobos","sequence":"additional","affiliation":[{"name":"Clinical Research Unit, Hospital Universitario \u201cDr. Jos\u00e9 Eleuterio Gonz\u00e1lez,\u201d Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo Le\u00f3n, M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario Alberto","family":"Campos-Coy","sequence":"additional","affiliation":[{"name":"Department of Radiology and Imaging, Faculty of Medicine, Hospital Universitario \u201cDr. Jos\u00e9 Eleuterio Gonz\u00e1lez,\u201d Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo Le\u00f3n, M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carla Melissa","family":"Ferrara-Chapa","sequence":"additional","affiliation":[{"name":"Department of Radiology and Imaging, Faculty of Medicine, Hospital Universitario \u201cDr. Jos\u00e9 Eleuterio Gonz\u00e1lez,\u201d Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo Le\u00f3n, M\u00e9xico"},{"name":"Department of Radiology and Imaging, Hospital General de Zona #33, Instituto Mexicano del Seguro Social, Monterrey, Nuevo Le\u00f3n, M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,2,16]]},"reference":[{"key":"bibr1-0284185120903449","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19831101)52:9<1551::AID-CNCR2820520902>3.0.CO;2-3"},{"key":"bibr2-0284185120903449","doi-asserted-by":"publisher","DOI":"10.1007\/s10434-999-0109-1"},{"key":"bibr3-0284185120903449","doi-asserted-by":"publisher","DOI":"10.3747\/co.22.2316"},{"key":"bibr4-0284185120903449","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.08.001"},{"key":"bibr5-0284185120903449","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2011.90"},{"key":"bibr6-0284185120903449","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.11470"},{"key":"bibr7-0284185120903449","doi-asserted-by":"publisher","DOI":"10.7863\/jum.1989.8.3.115"},{"key":"bibr8-0284185120903449","first-page":"612","volume":"108","author":"Chevinsky A","year":"1990","journal-title":"Surgery"},{"key":"bibr9-0284185120903449","first-page":"1034","volume-title":"Rosen\u2019s Breast Pathology","author":"Rosen PP.","year":"2009","edition":"3"},{"key":"bibr10-0284185120903449","first-page":"834","volume-title":". 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