{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T17:50:19Z","timestamp":1792086619615,"version":"4.4.0"},"reference-count":20,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2020,10,29]],"date-time":"2020-10-29T00:00:00Z","timestamp":1603929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Acta Radiol"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Reliable size measurement of lymph node (LN) metastases is important for the evaluation of cancer treatment. However, image analyses without proper settings may result in inappropriate diagnoses and staging.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To investigate whether reconstruction slice thickness in computed tomography (CT) affects measurements of LN size and reproducibility.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>We analyzed 48 patients with histological diagnoses of sigmoid colon and rectal cancer who underwent contrast-enhanced CT colonography as part of a surgical treatment preparation. A board-certified radiologist selected 106 LNs whose short-axis diameter was \u22655\u2009mm on 1-mm-thick images; the short-axis diameters were measured on 1- and 5-mm-thick images by the radiologist and residents and compared using Wilcoxon matched-pairs signed rank test. Data variation and reproducibility were evaluated using the F test and Bland\u2013Altman analysis. P&lt;0.05 was considered significant.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Short-axis diameters measured on 5-mm-thick images were significantly lower than those measured on 1-mm-thick images ( P&lt;0.01), even in the LNs whose short-axis diameters were over twice the slice thickness ( P&lt;0.05). Of the 106 LNs, 57 showed short-axis diameter &lt;5\u2009mm on 5-mm-thick images; the maximum short-axis diameter was 6.7\u2009mm on a 1-mm thick image. Data variation was significantly larger on 5-mm thick images than 1-mm-thick images in small LNs ( P&lt;0.05) and reproducibility on 5-mm-thick images was inferior to that on 1-mm-thick images.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Thick reconstruction slices in CT can result in an underestimation of LN size and reduce data reproducibility. When measuring LN size, a thin reconstruction slice would be recommended based on targeted LN size.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0284185120968569","type":"journal-article","created":{"date-parts":[[2020,10,30]],"date-time":"2020-10-30T01:12:58Z","timestamp":1604020378000},"page":"1275-1282","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["CT reconstruction with thick slices not only underestimates lymph node size but also reduces data reproducibility in colorectal cancer"],"prefix":"10.1177","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6991-288X","authenticated-orcid":false,"given":"Yurina","family":"Onuma","sequence":"first","affiliation":[{"name":"Department of Diagnostic Radiology, School of Medicine, Sapporo Medical University, Sapporo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chie","family":"Tsuruta","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, School of Medicine, Sapporo Medical University, Sapporo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"Okita","sequence":"additional","affiliation":[{"name":"Department of Surgery, Surgical Oncology and Science, School of Medicine, Sapporo Medical University, Sapporo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Hamabe","sequence":"additional","affiliation":[{"name":"Department of Surgery, Surgical Oncology and Science, School of Medicine, Sapporo Medical University, Sapporo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keishi","family":"Ogura","sequence":"additional","affiliation":[{"name":"Division of Radiology and Nuclear Medicine, Sapporo Medical University Hospital, Sapporo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ichiro","family":"Takemasa","sequence":"additional","affiliation":[{"name":"Department of Surgery, Surgical Oncology and Science, School of Medicine, Sapporo Medical University, Sapporo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4589-1578","authenticated-orcid":false,"given":"Masamitsu","family":"Hatakenaka","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, School of Medicine, Sapporo Medical University, Sapporo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,10,29]]},"reference":[{"key":"bibr1-0284185120968569","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i15.4244"},{"key":"bibr2-0284185120968569","doi-asserted-by":"publisher","DOI":"10.1177\/000313481508101230"},{"key":"bibr3-0284185120968569","first-page":"172","volume":"6","author":"Raman SP","year":"2015","journal-title":"J Gastrointest Oncol"},{"key":"bibr4-0284185120968569","doi-asserted-by":"publisher","DOI":"10.1120\/jacmp.v11i2.3037"},{"key":"bibr5-0284185120968569","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2008.10.026"},{"key":"bibr6-0284185120968569","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(12)70158-4"},{"key":"bibr7-0284185120968569","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2014.11.016"},{"issue":"39","key":"bibr8-0284185120968569","volume":"17","author":"Kumamoto T","year":"2019","journal-title":"World J Surg Oncol"},{"key":"bibr9-0284185120968569","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-009-0704-4"},{"key":"bibr10-0284185120968569","first-page":"12801","volume":"8","author":"Cui C","year":"2015","journal-title":"Int J Clin Exp Med"},{"key":"bibr11-0284185120968569","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2018.11.016"},{"key":"bibr12-0284185120968569","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-016-2641-3"},{"key":"bibr13-0284185120968569","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-015-5021-2"},{"key":"bibr14-0284185120968569","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-015-3299-7"},{"key":"bibr15-0284185120968569","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-015-2339-y"},{"key":"bibr16-0284185120968569","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v21.i2.556"},{"key":"bibr17-0284185120968569","doi-asserted-by":"publisher","DOI":"10.1148\/rg.262055138"},{"key":"bibr18-0284185120968569","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-011-2182-7"},{"key":"bibr19-0284185120968569","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2017.02.005"},{"key":"bibr20-0284185120968569","first-page":"625","volume":"10","author":"Sato K","year":"2019","journal-title":"Mol Clin Oncol"}],"container-title":["Acta Radiologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0284185120968569","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0284185120968569","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0284185120968569","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:26:41Z","timestamp":1777390001000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0284185120968569"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,29]]},"references-count":20,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2021,10]]}},"alternative-id":["10.1177\/0284185120968569"],"URL":"https:\/\/doi.org\/10.1177\/0284185120968569","relation":{},"ISSN":["0284-1851","1600-0455"],"issn-type":[{"value":"0284-1851","type":"print"},{"value":"1600-0455","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,29]]}}}