{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:36:56Z","timestamp":1777509416950,"version":"3.51.4"},"reference-count":10,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2025,7,10]],"date-time":"2025-07-10T00:00:00Z","timestamp":1752105600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Acta Radiol"],"published-print":{"date-parts":[[2025,11]]},"abstract":"\n Background<\/jats:title>\n Embolization plays a significant role in interventional radiology and modern medicine, intersecting with several specialties. The technological advancement of embolic agents has contributed to successful outcomes in the treatment of a wide range of diseases.<\/jats:p>\n <\/jats:sec>\n \n Purpose<\/jats:title>\n To compare the histomorphological effects of Embosoft microspheres and Embosphere microspheres in uterine artery embolization (UAE) in sheep.<\/jats:p>\n <\/jats:sec>\n \n Material and Methods<\/jats:title>\n \n Superselective and bilateral UAE was performed with Embosoft and Embosphere microspheres in 10 adult non-pregnant sheep. Embosoft microspheres with a diameter of 500\u2013700\u2005\u03bcm were compared with Embosphere microspheres of a similar diameter in two groups of five sheep each. One sheep was embolized only with non-ionic iodinated contrast solution and saline (SF0.9%). The evaluation was based on histopathological examination of the uterus, performed 7 days after embolization. Necrosis scores, the diameter of occluded arteries, and the number of particles were assessed. ANOVA test and Student's\n t<\/jats:italic>\n -test were used to determine the differences between the study groups.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n The mean volume of embolic agents was 18.35\u2005mL in the Embosphere group and 19.1\u2005mL in the Embosoft group, with no statistically significant difference (\n P<\/jats:italic>\n \u2009=\u20090.62). No significant difference was observed between the corresponding sides in the two groups. In addition, there were no significant differences in the thickness of the surface epithelium (Embosphere 21.26\u2005\u03bcm vs. 19.72\u2005\u03bcm Embosoft;\n P<\/jats:italic>\n \u2009=\u20090.56) and glandular area between the groups (Embosphere 12.20% vs. 17.77% Embosoft;\n P<\/jats:italic>\n \u2009=\u20090.18).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Embosoft micropheres were associated with a greater inflammatory response and a smaller area of degeneration compared to Embosphere microspheres.<\/jats:p>\n <\/jats:sec>","DOI":"10.1177\/02841851251355583","type":"journal-article","created":{"date-parts":[[2025,7,10]],"date-time":"2025-07-10T08:21:34Z","timestamp":1752135694000},"page":"1159-1164","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Uterine artery embolization in sheep: comparison of acute effects with Embosphere microspheres and Embosoft microspheres"],"prefix":"10.1177","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9427-5897","authenticated-orcid":false,"given":"T\u00falio Fabiano de Oliveira","family":"Leite","sequence":"first","affiliation":[{"name":"Interventional Radiology, Radiology Department, University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcos de Lorenzo","family":"Messina","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Hospital das Cl\u00ednicas, Faculty of Medicine, University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Celso Kiyochi","family":"Takimura","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology, Heart Institute (InCor), University of S\u00e3o Paulo Medical School, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mira Zlotnik","family":"Finkelstein","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Hospital das Cl\u00ednicas, Faculty of Medicine, University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose Maria Soares","family":"J\u00fanior","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Hospital das Cl\u00ednicas, Faculty of Medicine, University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9844-6833","authenticated-orcid":false,"given":"Joaquim Mauricio da Motta","family":"Leal Filho","sequence":"additional","affiliation":[{"name":"Interventional Radiology, Radiology Department, University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,7,10]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1914735"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00270-014-1045-4"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-69754-0"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(95)92282-2"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00270-013-0790-0"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00270-011-0228-5"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa062003"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2463070260"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1186\/s42155-021-00223-9"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.rli.0000188027.34400.f3"}],"container-title":["Acta Radiologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02841851251355583","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/02841851251355583","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02841851251355583","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:34:44Z","timestamp":1777390484000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/02841851251355583"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,10]]},"references-count":10,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["10.1177\/02841851251355583"],"URL":"https:\/\/doi.org\/10.1177\/02841851251355583","relation":{},"ISSN":["0284-1851","1600-0455"],"issn-type":[{"value":"0284-1851","type":"print"},{"value":"1600-0455","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,10]]}}}