{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:37:15Z","timestamp":1777509435187,"version":"3.51.4"},"reference-count":45,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T00:00:00Z","timestamp":1754956800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100005089","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","award":["7222029"],"award-info":[{"award-number":["7222029"]}],"id":[{"id":"10.13039\/501100005089","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82071882"],"award-info":[{"award-number":["82071882"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Acta Radiol"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Intracranial pressure is closely associated with pulsatile tinnitus (PT) caused by sigmoid sinus wall dehiscence (SSWD). Cerebrospinal fluid (CSF) plays a key role in regulating intracranial pressure; however, CSF alterations have not been reported in SSWD-PT patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate cardiac-driven CSF flow dynamics and volume changes in SSWD-PT patients with normal intracranial pressure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>SSWD-PT patients with normal intracranial pressure and age-, sex-, and handedness-matched healthy controls were prospectively enrolled and underwent MRI. Intracranial pressure was assessed using the index of transverse sinus stenosis and morphological changes. Cardiac-driven CSF flow dynamics were quantified by phase-contrast magnetic resonance imaging (MRI), and CSF volume was measured using ITK-SNAP segmentation software.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The study included 20 SSWD-PT patients and 35 controls. Compared with controls, the PT group showed a significant decrease in mean flux (MF) and a significant increase in regurgitant fraction (RF) (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u20090.043 and 0.008, respectively). No significant differences were observed in other parameters. The area under the curve (AUC), sensitivity, and specificity for MF and RF were 0.643, 100.0%, 31.4%, and 0.716, 50.0%, 88.6%, respectively. The combined diagnostic efficacy of MF and RF (AUC\u2009=\u20090.764) was higher than RF alone, though the difference was not significant (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u20090.390). The combined model and RF demonstrated significantly better diagnostic efficacy than MF (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u20090.025 and 0.045, respectively).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>SSWD-PT patients exhibited altered cardiac-driven CSF flow dynamics, which may contribute to PT. The combination of MF and RF may serve as a complementary index for identifying the underlying etiology of SSWD-PT.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/02841851251363702","type":"journal-article","created":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T07:09:50Z","timestamp":1754982590000},"page":"1235-1244","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Cerebrospinal fluid changes may be related to sigmoid sinus wall dehiscence-pulsatile tinnitus coexisting with normal intracranial pressure"],"prefix":"10.1177","volume":"66","author":[{"given":"Lanyue","family":"Chen","sequence":"first","affiliation":[{"name":"Beijing Tongren Hospital, Capital Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Radiology, Chonggang General Hospital, Chongqing, PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaobo","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoxia","family":"Qu","sequence":"additional","affiliation":[{"name":"Beijing Tongren Hospital, Capital Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dandan","family":"Zheng","sequence":"additional","affiliation":[{"name":"Philips (China) Investment Co., Ltd. Beijing Branch"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1317-3675","authenticated-orcid":false,"given":"Zhaohui","family":"Liu","sequence":"additional","affiliation":[{"name":"Beijing Tongren Hospital, Capital Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,8,12]]},"reference":[{"key":"e_1_3_2_2_2","first-page":"970613","article-title":"Temporal bone pneumatization and pulsatile tinnitus caused by sigmoid sinus diverticulum and\/or dehiscence","volume":"2015","author":"Liu W","year":"2015","unstructured":"Liu W, Liu Z, Zheng N, et al. Temporal bone pneumatization and pulsatile tinnitus caused by sigmoid sinus diverticulum and\/or dehiscence. Biomed Res Int 2015;2015:970613.","journal-title":"Biomed Res Int"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.31128\/AJGP-12-17-4420"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmpb.2020.105373"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e31822a1c7d"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e31829ab6d7"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1080\/00016480701840106"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1177\/0284185114559762"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.3109\/00016489.2013.831479"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1177\/0194599813520291"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1080\/00016489.2017.1385847"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2017.12.019"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-015-3827-8"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000002512"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/lary.27218"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00234-015-1517-5"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00234-018-1987-3"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A6043"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1177\/03000605231187949"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.1988.tb05888.x"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2012.02150.x"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1002\/ar.23514"},{"key":"e_1_3_2_23_2","first-page":"525","article-title":"Normal pressure hydrocephalus versus atrophic dilatation to distinguish and predict the benefits of surgical intervention with a phase-contrast MRI technique","volume":"24","author":"Aslan K","year":"2014","unstructured":"Aslan K, Tokatlioglu O, Aydin R, et al. Normal pressure hydrocephalus versus atrophic dilatation to distinguish and predict the benefits of surgical intervention with a phase-contrast MRI technique. Turk Neurosurg 2014;24:525\u2013531.","journal-title":"Turk Neurosurg"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00701-014-2109-6"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nrl.2013.02.016"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A3171"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2016-012605"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2012.02150.x"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11282-020-00426-1"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10278-019-00239-7"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2016.12.012"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12987-019-0129-6"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/97.1.301"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.20.8.787"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000005948"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0940-9602(98)80086-1"},{"key":"e_1_3_2_37_2","article-title":"Surgical treatment of pulsatile tinnitus caused by the sigmoid sinus diverticulum: a preliminary study","volume":"94","author":"Wang G","year":"2015","unstructured":"Wang G, Zeng R, Ma X, et al. Surgical treatment of pulsatile tinnitus caused by the sigmoid sinus diverticulum: a preliminary study. Medicine (Baltimore) 2015;94:e882.","journal-title":"Medicine (Baltimore)"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.3342\/ceo.2015.8.2.111"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e31829ab6d7"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1177\/0284185113481698"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2014.12.024"},{"key":"e_1_3_2_42_2","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2022.940140"},{"key":"e_1_3_2_43_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.aax5440"},{"key":"e_1_3_2_44_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2015.07.073"},{"key":"e_1_3_2_45_2","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.25591"},{"key":"e_1_3_2_46_2","doi-asserted-by":"publisher","DOI":"10.1111\/jon.70000"}],"container-title":["Acta Radiologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02841851251363702","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/02841851251363702","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02841851251363702","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:34:46Z","timestamp":1777390486000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/02841851251363702"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,12]]},"references-count":45,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["10.1177\/02841851251363702"],"URL":"https:\/\/doi.org\/10.1177\/02841851251363702","relation":{},"ISSN":["0284-1851","1600-0455"],"issn-type":[{"value":"0284-1851","type":"print"},{"value":"1600-0455","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,12]]}}}