{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:37:49Z","timestamp":1777509469700,"version":"3.51.4"},"reference-count":34,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T00:00:00Z","timestamp":1764201600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Acta Radiol"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>People diagnosed with cystic fibrosis (pwCF) who have chronic rhinosinusitis undergo low-dose computed tomography (LDCT) scans of the paranasal sinuses as a crucial component of their disease management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To assess and compare the intra-individual image quality and radiation dose between photon-counting CT (PCCT) and CT scanners utilizing an energy-integrating detector system (EID-CT) with LD protocols for pwCF.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>In this retrospective study, 23 pwCF who underwent LD paranasal sinuses PCCT and who had previously undergone LD paranasal sinuses EID-CT were included. An intra-individual comparison of image quality and radiation dose was carried out. Three blinded radiologists rated overall image quality, image sharpness, and image noise using a 5-point Likert scale. The study measured the dose length product, the volumetric CT dose index, the effective dose, and the signal to noise ratio (SNR).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The cohort comprised 23 individuals (6 women [26%], 17 men [74%]; mean age = 36.7 years). PCCT achieved superior evaluations for image quality in comparison to EID-CT (mean = 5 vs. 3;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;0.001). Furthermore, PCCT exhibited diminished image noise (mean = 4 vs. 3;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;0.001). The mean SNR of the paranasal sinuses demonstrated an increase in PCCT as opposed to EID-CT (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;0.001). PCCT demonstrated a reduction of approximately 36% in effective dose compared to EID-CT (mean = 0.09 vs. 0.15\u2005mSv;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>PCCT scans of the paranasal sinuses offer superior image quality and substantially reduce radiation dose compared to EID-CT scans in pwCF, offering a safer and more effective imaging alternative compared to EID-CT for managing cystic fibrosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/02841851251396564","type":"journal-article","created":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T18:29:58Z","timestamp":1764268198000},"page":"157-165","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Advancements in monitoring paranasal sinuses among people with cystic fibrosis using photon-counting CT"],"prefix":"10.1177","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-5250-5751","authenticated-orcid":false,"given":"Marko","family":"Frings","sequence":"first","affiliation":[{"name":"University Hospital Essen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdullatif","family":"Kocak","sequence":"additional","affiliation":[{"name":"University Hospital Essen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sivagurunathan","family":"Sutharsan","sequence":"additional","affiliation":[{"name":"University Hospital Essen \u2013 Ruhrlandklinik"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Forsting","sequence":"additional","affiliation":[{"name":"University Hospital Essen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Taube","sequence":"additional","affiliation":[{"name":"University Hospital Essen \u2013 Ruhrlandklinik"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7455-8590","authenticated-orcid":false,"given":"Marcel","family":"Opitz","sequence":"additional","affiliation":[{"name":"University Hospital Essen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias","family":"Welsner","sequence":"additional","affiliation":[{"name":"University Hospital Essen \u2013 Ruhrlandklinik"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,11,27]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.2475911"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.7543698"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1022430906284"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2015.10"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1300109"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2023.8120"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2018.04.036"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-014-3446-z"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-021-06875-6"},{"key":"e_1_3_3_11_2","first-page":"32","article-title":"Chronic Rhinosinusitis in cystic fibrosis: diagnosis and medical management","volume":"7","author":"Safi C","year":"2019","unstructured":"Safi C, Zheng Z, Dimango E, et al. 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