{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T18:14:14Z","timestamp":1778004854104,"version":"3.51.4"},"reference-count":27,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T00:00:00Z","timestamp":1773014400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100024075","name":"Region of Southern Denmark","doi-asserted-by":"crossref","award":["Grant Numbers: 16\/9780, 19\/37100"],"award-info":[{"award-number":["Grant Numbers: 16\/9780, 19\/37100"]}],"id":[{"id":"10.13039\/501100024075","id-type":"DOI","asserted-by":"crossref"}]},{"name":"The Danish Colitis and Crohn\u2019s Association","award":["Grant Number: 2017"],"award-info":[{"award-number":["Grant Number: 2017"]}]},{"name":"Research Council of Lillebaelt Hospital","award":["Grant Numbers:May 2016"],"award-info":[{"award-number":["Grant Numbers:May 2016"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Acta Radiol"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Magnetic resonance enterography (MRE) can visualize Crohn's disease (CD) and its complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To determine the inter-observer agreement for the detection of ileocolonic CD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>This post-hoc analysis included MRE scans from 48 patients selected from a prospective, blinded multicenter study of patients with suspected CD. Based on ileocolonoscopy in the main study, CD was diagnosed in 39 (81%) patients, with colonic involvement in 36 (69%). Two senior radiologists and two junior doctors undergoing specialist training, blinded to clinical data assessed the image quality, CD presence, and disease severity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The inter-observer agreement for CD detection varied by location: terminal ileum (\u03ba\u2009=\u20090.77, 95% confidence interval [CI] = 0.63\u20130.89), colon (\u03ba\u2009=\u20090.59, 95% CI = 0.42\u20130.74), and ileocolon (\u03ba\u2009=\u20090.65, 95% CI = 0.49\u20130.80). Agreement was higher among senior radiologists than juniors: terminal ileum (\u03ba\u2009=\u20090.83 vs. 0.73;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u20090.60) and colon (\u03ba\u2009=\u20090.73 vs. 0.41;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u20090.11), though differences were not statistically significant. The inter-observer agreement for disease severity was poor to moderate with intraclass correlation coefficients (ICCs) of 0.51 (95% CI = 0.35\u20130.67) for the MaRIA and 0.46 (95% CI = 0.29\u20130.62) for the simplified MaRIA. Senior radiologists showed higher consistency, with moderate to good agreement: ICC of 0.69 for the MaRIA, 0.70 for the simplified MaRIA, and 0.80 for bowel wall thickness.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In early CD, MRE demonstrated moderate to substantial inter-observer agreement for ileocolonic evaluation. Limitations in colonic assessment likely reflect early disease detection rather than observer variability, highlighting the need for a complementary assessment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/02841851261422702","type":"journal-article","created":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T11:02:33Z","timestamp":1773226953000},"page":"418-425","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Inter-observer variability for detection of suspected ileocolonic Crohn\u2019s disease with magnetic resonance enterography"],"prefix":"10.1177","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2530-7554","authenticated-orcid":false,"given":"Jacob Broder","family":"Brodersen","sequence":"first","affiliation":[{"name":"Esbjerg Hospital \u2013 University Hospital of Southern Denmark"},{"name":"University of Southern Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael Dam","family":"Jensen","sequence":"additional","affiliation":[{"name":"Esbjerg Hospital \u2013 University Hospital of Southern Denmark"},{"name":"University of Southern Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7538-3697","authenticated-orcid":false,"given":"Mathias","family":"Byriel","sequence":"additional","affiliation":[{"name":"University of Southern Denmark"},{"name":"Department of Radiology, Lillebaelt Hospital \u2013 University Hospital of Southern Denmark, Vejle, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claus","family":"Dam","sequence":"additional","affiliation":[{"name":"University of Southern Denmark"},{"name":"Department of Radiology, Lillebaelt Hospital \u2013 University Hospital of Southern Denmark, Vejle, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martina","family":"Loft","sequence":"additional","affiliation":[{"name":"University of Southern Denmark"},{"name":"Department of Radiology, Lillebaelt Hospital \u2013 University Hospital of Southern Denmark, Vejle, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5182-5545","authenticated-orcid":false,"given":"S\u00f8ren Rafael","family":"Rafaelsen","sequence":"additional","affiliation":[{"name":"University of Southern Denmark"},{"name":"Department of Radiology, Lillebaelt Hospital \u2013 University Hospital of Southern Denmark, Vejle, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,3,9]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)31711-1"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2022.07.062"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(18)30161-4"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.21551"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2008.167957"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-025-11620-2"},{"key":"e_1_3_3_8_2","doi-asserted-by":"crossref","unstructured":"Brodersen JB Knudsen T Kjeldsen J et al. 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