{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:35:13Z","timestamp":1792787713242,"version":"4.5.0"},"reference-count":32,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T00:00:00Z","timestamp":1787616000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"the National Natural Science Foundation of China","award":["82371979"],"award-info":[{"award-number":["82371979"]}],"id":[{"id":"https:\/\/ror.org\/01h0zpd94","id-type":"ROR","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2023YFC2410805"],"award-info":[{"award-number":["2023YFC2410805"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"name":"the Natural Science Foundation of Jiangsu Province","award":["BK20241983"],"award-info":[{"award-number":["BK20241983"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Acta Radiol"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Accurate staging is crucial for guiding treatment decisions and surgical planning in papillary thyroid carcinoma (PTC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To determine whether dual-energy computed tomography (DECT) can improve the accuracy of ultrasound (US) assessment for the 8th edition of the American Joint Committee on Cancer (AJCC) staging of PTC.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>This retrospective study included 325 patients with PTC who underwent US and DECT before radical thyroidectomy. Using pathological results as the reference standard, the diagnostic accuracy of US, DECT, and US\u2009+\u2009DECT assessments for primary tumor (pT), regional lymph node (pN), and AJCC 8th staging were compared. McNemar\u2019s test was used for head-to-head accuracy comparisons between DECT or US\u2009+\u2009DECT and US. Inter-observer agreement was assessed using intraclass correlation coefficients (ICCs).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      DECT showed significantly higher accuracy than US in pT evaluation (0.754 vs. 0.628;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;\u20090.001). DECT showed slightly higher accuracy than US in pN evaluation (0.662 vs. 0.652;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u20090.250). Combining DECT and US led to higher accuracy than US alone for both pT (0.655 vs. 0.628;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u20090.004) and pN (0.686 vs 0.652;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u20090.001) evaluation, specifically in T3b tumors (odds ratio [OR] 2.024;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u20090.043), T4 tumors (OR 8.125;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u20090.005), and N1b nodules (OR 2.027;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u20090.045). Combining DECT and US was associated with 95% higher odds of accuracy than US alone in AJCC 8th Stage II evaluation (OR 10.000;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u20090.041).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Combining DECT and US can improve US evaluation of pT and pN of PTC and the identification of Stage II PTC.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/02841851261477082","type":"journal-article","created":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T16:07:11Z","timestamp":1787674031000},"page":"831-840","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Added value of dual-energy CT to ultrasound assessment for AJCC 8th staging of papillary thyroid carcinoma"],"prefix":"10.1177","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8692-0902","authenticated-orcid":false,"given":"Yu","family":"Hu","sequence":"first","affiliation":[{"name":"Department of Medical Ultrasound, the First Affiliated Hospital with Nanjing Medical University, Nanjing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5493-5256","authenticated-orcid":false,"given":"Xiao-Quan","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Radiology, the First Affiliated Hospital with Nanjing Medical University, Nanjing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Ting","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Medical Ultrasound, the First Affiliated Hospital with Nanjing Medical University, Nanjing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0442-7170","authenticated-orcid":false,"given":"Ao","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Medical Ultrasound, the First Affiliated Hospital with Nanjing Medical University, Nanjing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Radiology, the First Affiliated Hospital with Nanjing Medical University, Nanjing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong-Kang","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Radiology, the First Affiliated Hospital with Nanjing Medical University, Nanjing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0343-0458","authenticated-orcid":false,"given":"Fei-Yun","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Radiology, the First Affiliated Hospital with Nanjing Medical University, Nanjing, 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