{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T12:00:06Z","timestamp":1777464006752,"version":"3.51.4"},"reference-count":11,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[1986,3,1]],"date-time":"1986-03-01T00:00:00Z","timestamp":510019200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Radiologica. Diagnosis"],"published-print":{"date-parts":[[1986,3]]},"abstract":"<jats:p>\n                    The adult respiratory distress syndrome was induced in pigs (n=11) by a continuous infusion of E. coli endotoxin in order to evaluate the use of radiographic videodensitometry and chest radiography for assessment of pulmonary circulation and pulmonary oedema. A further aim was to determine the effect of an ionic contrast medium, Urografin 60%, on extravascular lung water (EVLW). The infusion resulted in a decline in arterial oxygen tension. Mean pulmonary arterial pressure increased, and cardiac output decreased, resulting in a marked rise in pulmonary vascular resistance. EVLW increased moderately. The corresponding variables in control animals (saline infusion; n=5) changed very little. Good correlations were found (r=0.87\u20131.0) between absolute flows as measured by the thermodilution technique and relative flows as determined by videodensitometry in animals with pulmonary damage. In the endotoxin group there was a significant correlation (r=0.75) between the change in EVLW from baseline to the final measurement (at 6 hours) and the corresponding change in radiographic density. Radiographic signs of pulmonary damage were sparse. Only 3 of 11 animals displayed increased radiographic density of the lung parenchyma indicative of pulmonary oedema. Pleural effusion developed in 4 animals. Injection of Urografin 60%, 1 ml\u00d7kg\n                    <jats:sup>1<\/jats:sup>\n                    , caused a slight but significant decrease in EVLW. We propose that at this concentration and dosage the contrast medium acts mainly as an osmotic diuretic.\n                  <\/jats:p>","DOI":"10.1177\/028418518602700221","type":"journal-article","created":{"date-parts":[[2015,6,11]],"date-time":"2015-06-11T06:25:56Z","timestamp":1434003956000},"page":"249-256","source":"Crossref","is-referenced-by-count":1,"title":["Videodensitometry and Chest Radiography in the Evaluation of Pulmonary Blood Flow and Pulmonary Oedema in a Porcine Model of Early Adult Respiratory Distress Syndrome"],"prefix":"10.1177","volume":"27","author":[{"given":"G.","family":"Wegenius","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Forsgren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Modig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1986,3,1]]},"reference":[{"key":"bibr1-028418518602700221","doi-asserted-by":"publisher","DOI":"10.3109\/03009737409178396"},{"key":"bibr2-028418518602700221","doi-asserted-by":"crossref","unstructured":"Borg T., Alvfors A., Gerdin B., Modig J.: A porcine model of early adult respiratory distress syndrome induced by endotoxaemia. To be published in Acta Anaesthesiol. Scand. (1985).","DOI":"10.1111\/j.1399-6576.1985.tb02306.x"},{"key":"bibr3-028418518602700221","first-page":"663","volume":"16","author":"Erikson U.","year":"1980","journal-title":"Bull. Europ. Physiopathol. Respir."},{"key":"bibr4-028418518602700221","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/54.7.723"},{"key":"bibr5-028418518602700221","first-page":"179","volume":"140","author":"Fulton R. L.","year":"1975","journal-title":"Surg. Gynec. Obstet."},{"key":"bibr6-028418518602700221","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1982.tb21388.x"},{"key":"bibr7-028418518602700221","doi-asserted-by":"publisher","DOI":"10.1177\/028418518302400512"},{"key":"bibr8-028418518602700221","first-page":"315","author":"Modig J.","year":"1985","journal-title":"Acta Chir. Scand."},{"key":"bibr9-028418518602700221","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.1983.tb01970.x"},{"key":"bibr10-028418518602700221","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-198405000-00010"},{"key":"bibr11-028418518602700221","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.10.3.393"}],"container-title":["Acta Radiologica. Diagnosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/028418518602700221","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/028418518602700221","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T13:22:12Z","timestamp":1777382532000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/028418518602700221"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,3]]},"references-count":11,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1986,3]]}},"alternative-id":["10.1177\/028418518602700221"],"URL":"https:\/\/doi.org\/10.1177\/028418518602700221","relation":{},"ISSN":["0567-8056"],"issn-type":[{"value":"0567-8056","type":"print"}],"subject":[],"published":{"date-parts":[[1986,3]]}}}