{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:26:06Z","timestamp":1777728366421,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2013,5,17]],"date-time":"2013-05-17T00:00:00Z","timestamp":1368748800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      This study investigated the influence of laparoscopic carbon dioxide (CO\n                      <jats:sub>2<\/jats:sub>\n                      ) pneumoperitoneum on neonate circulation and respiration.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      The study included neonates undergoing elective laparoscopic abdominal surgery. CO\n                      <jats:sub>2<\/jats:sub>\n                      insufflation pressure was maintained within 8\u201314\u2009mmHg for pneumoperitoneum creation. Heart rate (HR), mean arterial pressure (MAP), peripheral oxygen saturation (SpO\n                      <jats:sub>2<\/jats:sub>\n                      ), partial pressure of end-tidal carbon dioxide ( P\n                      <jats:sub>ET<\/jats:sub>\n                      CO\n                      <jats:sub>2<\/jats:sub>\n                      ) and maximum inspiratory pressure were monitored continuously. Arterial blood samples were collected: 5\u2009min before pneumoperitoneum creation (baseline); 5, 10, and 20\u2009min after CO\n                      <jats:sub>2<\/jats:sub>\n                      insufflation; 10\u2009min after CO\n                      <jats:sub>2<\/jats:sub>\n                      exsufflation; 10\u2009min after surgery. pH, partial pressure of CO\n                      <jats:sub>2<\/jats:sub>\n                      (PaCO\n                      <jats:sub>2<\/jats:sub>\n                      ) and arterial oxygen saturation (SaO\n                      <jats:sub>2<\/jats:sub>\n                      ) were also measured.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Thirty-six neonates were included. HR and MAP significantly increased after pneumoperitoneum creation, then decreased to baseline after CO\n                      <jats:sub>2<\/jats:sub>\n                      exsufflation. PaCO\n                      <jats:sub>2<\/jats:sub>\n                      and P\n                      <jats:sub>ET<\/jats:sub>\n                      CO\n                      <jats:sub>2<\/jats:sub>\n                      were significantly higher after pneumoperitoneum creation, whereas pH was significantly lower 20\u2009min after pneumoperitoneum creation compared with baseline. No significant differences were observed in SpO\n                      <jats:sub>2<\/jats:sub>\n                      and SaO\n                      <jats:sub>2<\/jats:sub>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      CO\n                      <jats:sub>2<\/jats:sub>\n                      pneumoperitoneum had a significant effect on neonatal circulation and respiration, suggesting that the pneumoperitoneal pressure should be limited within a certain range in neonates undergoing laparoscopic surgery.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0300060513481922","type":"journal-article","created":{"date-parts":[[2013,5,18]],"date-time":"2013-05-18T00:24:16Z","timestamp":1368836656000},"page":"889-894","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Influence of laparoscopic carbon dioxide pneumoperitoneum on neonate circulation and respiration"],"prefix":"10.1177","volume":"41","author":[{"given":"Li-Wei","family":"Li","sequence":"first","affiliation":[{"name":"Department of Anaesthesiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, 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