{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:27:04Z","timestamp":1777728424487,"version":"3.51.4"},"reference-count":31,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2013,5,21]],"date-time":"2013-05-21T00:00:00Z","timestamp":1369094400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To determine the efficacy of botulinum toxin-A (BTX-A) nerve block, with and without rehabilitation, in the treatment of spastic cerebral palsy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients (aged 1\u201323 years) with spastic cerebral palsy underwent nerve block with BTX-A, followed by\u2009\u2265\u20092\u2009h\/day rehabilitation (experimental group) or &lt;2\u2009h\/day rehabilitation (control group). Muscle tension and motor function were evaluated pre-block using the Modified Ashworth Scale (MAS) and gross motor function measure (GMFM), respectively. MAS was assessed weekly to determine duration of action of BTX-A; GMFM was assessed at 1 year post-block.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>There were no significant differences between the experimental group ( n\u2009=\u2009120) and the control group ( n\u2009=\u2009124) in age, body weight, pre-block MAS or GMFM, or BTX-A duration of action. MAS was significantly improved in both groups at 1 month post-block. At 1 year post-block, GMFM was significantly improved in both groups, with a significantly greater improvement seen in the experimental group compared with the control group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>BTX-A block improved muscle tension and motor function. Rehabilitation training, following the block, resulted in greater improvements to motor function than block alone.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0300060513488515","type":"journal-article","created":{"date-parts":[[2013,5,21]],"date-time":"2013-05-21T20:19:37Z","timestamp":1369167577000},"page":"636-641","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Botulinum toxin-A with and without rehabilitation for the treatment of spastic cerebral palsy"],"prefix":"10.1177","volume":"41","author":[{"given":"Liu","family":"Jianjun","sequence":"first","affiliation":[{"name":"Capital Medical University School of Rehabilitation Medicine, China Rehabilitation Research Centre, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji","family":"Shurong","sequence":"additional","affiliation":[{"name":"Capital Medical University School of Rehabilitation Medicine, China 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