{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:27:05Z","timestamp":1777728425908,"version":"3.51.4"},"reference-count":14,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2013,8,9]],"date-time":"2013-08-09T00:00:00Z","timestamp":1376006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2013,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate the postoperative analgesic effects of parecoxib for uvulopalatopharyngoplasty (UPPP).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients with obstructive sleep apnoea syndrome who underwent UPPP were randomly divided into two groups. In group A, the incision-local block was performed with 5\u2009ml of 0.5% ropivacaine injected subcutaneously before the end of surgery, then 20\u2009ml of physiological saline was injected intravenously every 12\u2009h for 2 days. In group B, in addition to the incision-local block, 40\u2009mg parecoxib was injected intravenously 30\u2009min before the end of UPPP and 40\u2009mg parecoxib was injected intravenously every 12\u2009h for 2 days. Postoperative pain was measured using a visual analogue scale (VAS). Adverse reactions were recorded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 40 patients were randomized (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u200920 per group). Under resting conditions, the mean\u2009\u00b1\u2009SD VAS pain scores were significantly higher in group A compared with group B at 24\u2009h and 48\u2009h after UPPP (24\u2009h 4.0\u2009\u00b1\u20090.8 versus 2.6\u2009\u00b1\u20090.6; 48\u2009h 3.8\u2009\u00b1\u20090.7 versus 2.4\u2009\u00b1\u20090.5; respectively). Under swallowing conditions, the mean\u2009\u00b1\u2009SD VAS pain scores were significantly higher in group A compared with group B at 8\u2009h, 24\u2009h and 48\u2009h after UPPP. Postoperative adverse reactions were similar in the two groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Intravenous parecoxib combined with incision-local ropivacaine provided effective postoperative analgesia for patients with obstructive sleep apnoea syndrome, undergoing UPPP.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0300060513489473","type":"journal-article","created":{"date-parts":[[2013,8,9]],"date-time":"2013-08-09T23:59:15Z","timestamp":1376092755000},"page":"1699-1704","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Application of parecoxib in post-uvulopalatopharyngoplasty analgesia"],"prefix":"10.1177","volume":"41","author":[{"given":"Guang-Lun","family":"Xie","sequence":"first","affiliation":[{"name":"Department of Anaesthesiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qin-Jun","family":"Chu","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chun-Lan","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2013,8,9]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1177\/147323000703500304"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1177\/147323001103900523"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/64.4.446"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-59980301579-1"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40266-012-0047-7"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.163.3.2005065"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/22.6.740"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.94.1.9"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.3109\/00016480802654380"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200605000-00026"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000173199.57456.2b"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-1716.2012.02411.x"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200603000-00020"},{"key":"e_1_3_3_15_2","first-page":"336","article-title":"Intravenous parecoxib sodium for acute pain after orthopedic knee surgery","volume":"31","author":"Rasmussen GL","year":"2002","unstructured":"Rasmussen GL, Steckner K, Hogue C, et al. Intravenous parecoxib sodium for acute pain after orthopedic knee surgery. Am J Orthop (Belle Mead NJ) 2002; 31: 336\u2013343.","journal-title":"Am J Orthop (Belle Mead NJ)"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300060513489473","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0300060513489473","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300060513489473","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:52:03Z","timestamp":1777459923000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0300060513489473"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8,9]]},"references-count":14,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013,10]]}},"alternative-id":["10.1177\/0300060513489473"],"URL":"https:\/\/doi.org\/10.1177\/0300060513489473","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,8,9]]}}}