{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:28:49Z","timestamp":1777728529712,"version":"3.51.4"},"reference-count":38,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2014,2,25]],"date-time":"2014-02-25T00:00:00Z","timestamp":1393286400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"},{"start":{"date-parts":[[2014,2,25]],"date-time":"2014-02-25T00:00:00Z","timestamp":1393286400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate the renoprotective effect of nicardipine in patients with pre-existing renal insufficiency undergoing robot-assisted laparoscopic radical prostatectomy (RALRP).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Men with preoperative renal insufficiency (estimated glomerular filtration rate [eGFR] &lt;60\u2009ml\/min per 1.73\u2009m\n                      <jats:sup>2<\/jats:sup>\n                      ) were enrolled and randomized to receive either 0.5\u2009\u00b5g\/kg per min nicardipine continuous infusion (nicardipine group) or normal saline (control group) during RALRP. Renal function was determined by eGFR and serum creatinine concentration.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Serum creatinine levels on postoperative days (POD) 1 and 3 were significantly lower than baseline values in the nicardipine group (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u200950). In the control group (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u200950), eGFR was significantly higher on POD 3 than baseline, and was significantly higher than baseline on POD 1 and 3 in the nicardipine group. The change in eGFR from baseline to POD 1 was significantly higher in the nicardipine group than the control group.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Continuous infusion of nicardipine during RALRP improved postoperative renal function on POD 1 in patients with pre-existing renal insufficiency.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0300060513510435","type":"journal-article","created":{"date-parts":[[2014,2,25]],"date-time":"2014-02-25T23:49:04Z","timestamp":1393372144000},"page":"427-435","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Effect of nicardipine on renal function following robot-assisted laparoscopic radical prostatectomy in patients with pre-existing renal insufficiency"],"prefix":"10.1177","volume":"42","author":[{"given":"Hyub","family":"Huh","sequence":"first","affiliation":[{"name":"Department of Anaesthesia and Pain Medicine, Anam Hospital, Korea University, Seoul, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Na Young","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Pain Medicine, Yonsei University, Seoul, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seol Ju","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Pain Medicine, Anam Hospital, Korea University, Seoul, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jang Eun","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Pain Medicine, Anam Hospital, Korea University, Seoul, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2014,2,25]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2006.11.031"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1089\/end.2010.0680"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004649900466"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-001-9201-8"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2011.03.040"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5049.115607"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005344-198303000-00015"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01744743"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2008.08.490"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2431-7-27"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0b013e318287b72c"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1994.00420150030004"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1089\/end.2010.0680"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aeq018"},{"key":"e_1_3_3_16_2","first-page":"317","article-title":"The effect of prolonged pneumoperitoneum on renal function in an animal model","volume":"182","author":"McDougall EM","year":"1996","unstructured":"McDougall EM, Monk TG, Wolf JS Jr, et al. 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