{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:28:58Z","timestamp":1777728538862,"version":"3.51.4"},"reference-count":30,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2014,3,20]],"date-time":"2014-03-20T00:00:00Z","timestamp":1395273600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate the prevalence of hypertension and circadian blood pressure (BP) variations in patients with obstructive sleep apnoea\u2013hypopnoea syndrome (OSAHS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Patients referred to a sleep clinic underwent polysomnography with measurement of BP at four time points. They were classified into four groups (control, and mild, moderate or severe sleep apnoea) using the apnoea\u2013hypopnoea index (AHI). Circadian variation was assessed using night-time to daytime mean BP ( R\n                      <jats:sub>N\/D<\/jats:sub>\n                      ) and morning to evening mean BP ( R\n                      <jats:sub>M\/E<\/jats:sub>\n                      ) ratios.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Hypertension was significantly more common in patients with OSAHS (50.5%) than in controls (30.4%). AHI was positively correlated with hypertension after controlling for related confounders. Mean BP values at all four time points rose with increasing AHI. The increase in night-time and morning values was more pronounced than the increase in daytime and evening values in patients with OSAHS, resulting in loss of the normal BP diurnal rhythm. The R\n                      <jats:sub>N\/D<\/jats:sub>\n                      and R\n                      <jats:sub>M\/E<\/jats:sub>\n                      ratios increased with increasing AHI. Daytime BP was significantly correlated with AHI and the lowest oxygen saturation value.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>OSAHS was shown to be an independent risk factor for hypertension. It was also associated with loss of the normal BP diurnal rhythm.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0300060513516756","type":"journal-article","created":{"date-parts":[[2014,3,20]],"date-time":"2014-03-20T21:56:59Z","timestamp":1395352619000},"page":"773-780","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":15,"title":["Prevalence of hypertension and circadian blood pressure variations in patients with obstructive sleep apnoea\u2013hypopnoea syndrome"],"prefix":"10.1177","volume":"42","author":[{"given":"Yan","family":"Wang","sequence":"first","affiliation":[{"name":"Respiratory Department, Tianjin Medical University General Hospital, Tianjin, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caili","family":"Li","sequence":"additional","affiliation":[{"name":"Graduate School, Tianjin Medical University, Tianjin, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liting","family":"Feng","sequence":"additional","affiliation":[{"name":"Respiratory Department, Tianjin Medical University General Hospital, Tianjin, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Feng","sequence":"additional","affiliation":[{"name":"Respiratory Department, Tianjin Medical University General Hospital, Tianjin, China"},{"name":"Division of Pulmonary and Critical Care Medicine, Duke University Medical Center, Durham, NC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Cao","sequence":"additional","affiliation":[{"name":"Respiratory Department, Tianjin Medical University General Hospital, Tianjin, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baoyuan","family":"Chen","sequence":"additional","affiliation":[{"name":"Respiratory Department, Tianjin Medical University General Hospital, Tianjin, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2014,3,20]]},"reference":[{"key":"bibr1-0300060513516756","doi-asserted-by":"crossref","first-page":"2541","DOI":"10.1002\/cphy.c110064","volume":"2","author":"White DP","year":"2012","journal-title":"Compr Physiol"},{"key":"bibr2-0300060513516756","doi-asserted-by":"publisher","DOI":"10.1001\/jama.283.14.1829"},{"key":"bibr3-0300060513516756","doi-asserted-by":"publisher","DOI":"10.1111\/j.1745-7599.2012.00771.x"},{"key":"bibr4-0300060513516756","first-page":"1740","volume":"125","author":"He QY","year":"2012","journal-title":"Chin Med J (Engl)"},{"key":"bibr5-0300060513516756","doi-asserted-by":"publisher","DOI":"10.1007\/s11325-010-0337-4"},{"key":"bibr6-0300060513516756","doi-asserted-by":"publisher","DOI":"10.1097\/01.hjh.0000431740.32696.cc"},{"key":"bibr7-0300060513516756","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2012.02.041"},{"key":"bibr8-0300060513516756","first-page":"425","volume":"35","author":"Thornton AT","year":"2012","journal-title":"Sleep"},{"key":"bibr9-0300060513516756","doi-asserted-by":"publisher","DOI":"10.1038\/hr.2010.153"},{"key":"bibr10-0300060513516756","doi-asserted-by":"publisher","DOI":"10.3109\/03009734.2012.707253"},{"key":"bibr11-0300060513516756","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(12)70051-6"},{"key":"bibr12-0300060513516756","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.12.050"},{"key":"bibr13-0300060513516756","doi-asserted-by":"publisher","DOI":"10.1111\/j.1582-4934.2009.00929.x"},{"key":"bibr14-0300060513516756","unstructured":"Sarigianni M, Dimitrakopoulos K and Tsapas A. 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