{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:30:19Z","timestamp":1777728619765,"version":"3.51.4"},"reference-count":30,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2014,11,6]],"date-time":"2014-11-06T00:00:00Z","timestamp":1415232000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2015,2]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the impact of the peritoneal glucose load (PGL) on hydration status and inflammation in peritoneal dialysis (PD) patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This cross-sectional study evaluated stable PD patients using a novel PGL index (PGLI), which was calculated as the net glucose content (g) in the PD solutions administered in the daily PD prescription divided by the dry body weight (kg) assessed by whole-body bioimpedance spectroscopy. The relationship between PGLI and glycosylated haemoglobin (HbA\n                      <jats:sub>1c<\/jats:sub>\n                      ), fluid overload (FO), and inflammatory markers was investigated.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 43 stable PD patients participated in the study. Significant positive correlations were found between PGLI and HbA\n                      <jats:sub>1c<\/jats:sub>\n                      , FO, plasma high sensitivity C-reactive protein (hsCRP), and plasma interleukin-6 (IL-6) levels. HbA\n                      <jats:sub>1c<\/jats:sub>\n                      , FO, plasma hsCRP and plasma IL-6 levels were significantly higher in patients with PGLI &gt;3\u2009g\/kg\/day compared with those with PGLI \u22643\u2009g\/kg\/day.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>PGLI values &gt;3\u2009g\/kg\/day may be associated with poor glycaemic control, over hydration and augmented inflammation. PGLI might be a useful tool for the quantitative assessment of the PGL and could be applied when managing PD patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0300060514550013","type":"journal-article","created":{"date-parts":[[2014,11,7]],"date-time":"2014-11-07T04:55:20Z","timestamp":1415336120000},"page":"42-53","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["The impact of the peritoneal glucose load index on hydration status and inflammation in peritoneal dialysis patients"],"prefix":"10.1177","volume":"43","author":[{"given":"Kamal","family":"Hassan","sequence":"first","affiliation":[{"name":"Faculty of Medicine in the Galilee, Bar-Ilan University, Safed, Israel"},{"name":"Department of Nephrology and Hypertension, Peritoneal Dialysis Unit, Western Galilee Hospital, Nahariya, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fadi","family":"Hassan","sequence":"additional","affiliation":[{"name":"Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rabia","family":"Edgem","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Hypertension, Peritoneal Dialysis Unit, Western Galilee Hospital, Nahariya, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Smadar","family":"Moshe","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Hypertension, Peritoneal Dialysis Unit, Western Galilee Hospital, Nahariya, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shadi","family":"Hassan","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Carmel Medical Centre, Haifa, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2014,11,6]]},"reference":[{"key":"bibr1-0300060514550013","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfh103"},{"key":"bibr2-0300060514550013","doi-asserted-by":"publisher","DOI":"10.1016\/j.semnephrol.2011.01.005"},{"key":"bibr3-0300060514550013","first-page":"839","volume-title":"Comprehensive clinical nephrology","author":"Stenvinkel P","year":"2007","edition":"3"},{"key":"bibr4-0300060514550013","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa021778"},{"key":"bibr5-0300060514550013","doi-asserted-by":"crossref","unstructured":"United States Renal Data System: Excerpts from the USRDS 2005 Annual Data Report. 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