{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:30:35Z","timestamp":1777728635836,"version":"3.51.4"},"reference-count":20,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2015,3,18]],"date-time":"2015-03-18T00:00:00Z","timestamp":1426636800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate retinal maturation in premature infants (gestation age &lt;37 weeks). using computer-assisted indirect ophthalmoscope imaging.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Premature infants at postmenstrual age 33\u201346 weeks, who underwent fundus examinations using computer-aided indirect ophthalmoscopy, were stratified into seven postmenstrual-age groups. Images of macular morphology, peripheral retinal vascularization and fundus pigmentation were compared.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The study included 268 infants in the following postmenstrual-age groups: 33\u201334 weeks ( n\u2009=\u200919), 35\u201336 weeks ( n\u2009=\u200937), 37\u201338 weeks ( n\u2009=\u200949), 39\u201340 weeks ( n\u2009=\u200955), 41\u201342 weeks ( n\u2009=\u200949), 43\u201344 weeks ( n\u2009=\u200934), and 45\u201346 weeks ( n\u2009=\u200925). The macula matured with increasing postmenstrual age. A mature macula was observed in 92% of infants at 45\u201346 weeks. Complete vascularization was achieved at 41\u201342 weeks in the nasal retina and at 43\u201344 weeks in the temporal retina. The number of retinas with normal pigmentation increased with postmenstrual age (rising to 84% of infants at postmenstrual age 45\u201346 weeks).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Following premature birth, macular morphology, retinal vascularization and retinal pigmentation continue to develop. This study provides reference images of normal retinal development in premature infants.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0300060514563152","type":"journal-article","created":{"date-parts":[[2015,3,18]],"date-time":"2015-03-18T21:55:12Z","timestamp":1426715712000},"page":"393-401","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Morphological features of retinal development in premature Chinese infants observed by computer-assisted indirect ophthalmoscope imaging"],"prefix":"10.1177","volume":"43","author":[{"given":"Feng","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Paediatric Ophthalmology, Guangzhou Women and Children\u2019s Medical Centre, Guangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daoman","family":"Xiang","sequence":"additional","affiliation":[{"name":"Department of Paediatric Ophthalmology, Guangzhou Women and Children\u2019s Medical Centre, Guangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yani","family":"Mao","sequence":"additional","affiliation":[{"name":"Department of Paediatric Ophthalmology, Guangzhou Women and Children\u2019s Medical Centre, Guangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tian","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Paediatric Ophthalmology, Guangzhou Women and Children\u2019s Medical Centre, Guangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2015,3,18]]},"reference":[{"key":"bibr1-0300060514563152","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(97)01107-0"},{"key":"bibr2-0300060514563152","doi-asserted-by":"publisher","DOI":"10.1097\/MOP.0b013e3283423f35"},{"key":"bibr3-0300060514563152","first-page":"S107","volume":"95","author":"Warrasak S","year":"2012","journal-title":"J Med Assoc Thai"},{"key":"bibr4-0300060514563152","first-page":"233","volume":"102","author":"Good WV","year":"2004","journal-title":"Trans Am Ophthalmol Soc"},{"key":"bibr5-0300060514563152","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2013.128"},{"key":"bibr6-0300060514563152","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2008.148908"},{"key":"bibr7-0300060514563152","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaapos.2013.10.018"},{"key":"bibr8-0300060514563152","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2012-302066"},{"key":"bibr9-0300060514563152","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2012.712313"},{"key":"bibr10-0300060514563152","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1984.01040030908011"},{"key":"bibr11-0300060514563152","first-page":"2205","author":"Fu SJ","year":"1996","journal-title":"Ophthalmology f. 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