{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T00:34:08Z","timestamp":1793234048846,"version":"4.5.0"},"reference-count":23,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2015,5,22]],"date-time":"2015-05-22T00:00:00Z","timestamp":1432252800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To develop a Web-based tool to draw attention to patients positive for human papillomavirus (HPV) who have a high risk of progression to cervical cancer, in order to increase compliance with follow-up examinations and facilitate good doctor\u2013patient communication.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Records were retrospectively analysed from women who were positive for HPV on initial testing (before any treatment). Information concerning age, Papanicolaou (PAP) smear result and presence of 15 high-risk HPV genotypes was used in a support vector machine (SVM) model, to identify the patient features that maximally contributed to progression to high-risk cervical lesions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Data from 731 subjects were analysed. The maximum number of correct cancer predictions was seen when four features (PAP, HPV16, HPV52 and HPV35) were used, giving an accuracy of 74.41%. A web-based high-risk cervical lesion prediction application tool was developed using the SVM model results.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Use of the web-based prediction tool may help to increase patient compliance with physician advice, and may heighten awareness of the significance of regular follow-up HPV examinations for the prevention of cervical cancer, in Korean women predicted to have heightened risk of the disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0300060515577846","type":"journal-article","created":{"date-parts":[[2015,5,22]],"date-time":"2015-05-22T22:20:45Z","timestamp":1432333245000},"page":"518-525","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":15,"title":["Development of a cervical cancer progress prediction tool for human papillomavirus-positive Koreans: A support vector machine-based approach"],"prefix":"10.1177","volume":"43","author":[{"given":"Jimin","family":"Kahng","sequence":"first","affiliation":[{"name":"Department of Laboratory Medicine, College of Medicine, Catholic University of Korea, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eung-Hee","family":"Kim","sequence":"additional","affiliation":[{"name":"Biomedical Knowledge Engineering Laboratory, Seoul National University, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong-Gee","family":"Kim","sequence":"additional","affiliation":[{"name":"Biomedical Knowledge Engineering Laboratory, Seoul National University, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wonbae","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, College of Medicine, Catholic University of Korea, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2015,5,22]]},"reference":[{"key":"bibr1-0300060515577846","doi-asserted-by":"publisher","DOI":"10.3322\/caac.20107"},{"key":"bibr2-0300060515577846","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2012.03.047"},{"key":"bibr3-0300060515577846","doi-asserted-by":"publisher","DOI":"10.1038\/nrc798"},{"key":"bibr4-0300060515577846","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.25396"},{"key":"bibr5-0300060515577846","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199802123380703"},{"key":"bibr6-0300060515577846","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2007.07.067"},{"key":"bibr7-0300060515577846","first-page":"47","volume":"1996","author":"Morris M","year":"1996","journal-title":"J Natl Cancer Inst Monogr"},{"key":"bibr8-0300060515577846","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.1993.1271"},{"key":"bibr9-0300060515577846","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-13-553"},{"key":"bibr10-0300060515577846","unstructured":"American Cancer Society. 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