{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:38:17Z","timestamp":1777729097574,"version":"3.51.4"},"reference-count":38,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2017,6,6]],"date-time":"2017-06-06T00:00:00Z","timestamp":1496707200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21377052"],"award-info":[{"award-number":["21377052"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81572512"],"award-info":[{"award-number":["81572512"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To analyze the postoperative recurrence of renal cell carcinoma associated with Xp11.2 translocation\/TFE3 gene fusion (Xp11.2 tRCC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective study was approved by the institutional review board and performed in accordance with the ethical standards established by the institution. Demographic, clinical, pathological, and follow-up data were compiled for the study cohort.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>During a mean follow-up of 41.3 months (range, 3\u2013104 months), 8 of 34 patients with Xp11.2 tRCC were confirmed to have recurrence. Three of these patients died with poor outcomes due to a vena cava tumor embolus, and one died of distant metastasis 48 months after the initial nephrectomy during which lymph node metastasis was found. Three patients survived after cytoreduction surgery. One patient was diagnosed with lung metastasis 11 months postoperatively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The TNM classification provides significant prognostic information for Xp11.2 tRCC. A relatively active surveillance algorithm is recommended, and cytoreduction surgery is an effective approach for recurrent Xp11.2 tRCC. Larger studies are required to more extensively investigate the recurrence of these potentially aggressive tumors.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0300060517711358","type":"journal-article","created":{"date-parts":[[2017,6,7]],"date-time":"2017-06-07T02:06:09Z","timestamp":1496801169000},"page":"1287-1296","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Postoperative recurrence of adult renal cell carcinoma associated with Xp11.2 translocation\/TFE3 gene fusion"],"prefix":"10.1177","volume":"45","author":[{"given":"Zhen","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Urology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu Province, CN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ning","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Urology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu Province, CN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weidong","family":"Gan","sequence":"additional","affiliation":[{"name":"Department of Urology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu Province, CN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaogong","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Urology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu Province, CN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gutian","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Urology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu Province, CN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dongmei","family":"Li","sequence":"additional","affiliation":[{"name":"Immunology and Reproductive Biology Laboratory & State Key Laboratory of Analytical Chemistry for Life Science, Medical School, Nanjing University, Nanjing, Jiangsu Province, CN"},{"name":"Jiangsu Key Laboratory of Molecular Medicine, Nanjing University, Nanjing, Jiangsu Province, CN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongqian","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Urology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu Province, CN"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,6,6]]},"reference":[{"key":"bibr1-0300060517711358","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2005.11.035"},{"key":"bibr2-0300060517711358","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e318299f2d1"},{"key":"bibr3-0300060517711358","doi-asserted-by":"publisher","DOI":"10.2478\/raon-2013-0077"},{"key":"bibr4-0300060517711358","doi-asserted-by":"publisher","DOI":"10.1186\/s12894-015-0055-0"},{"key":"bibr5-0300060517711358","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.5858\/133.7.1026","volume":"133","author":"Yan BC","year":"2009","journal-title":"Arch Pathol Lab Med"},{"key":"bibr6-0300060517711358","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e31818fbdff"},{"key":"bibr7-0300060517711358","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181609914"},{"key":"bibr8-0300060517711358","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000000873"},{"key":"bibr9-0300060517711358","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2012.07.051"},{"key":"bibr10-0300060517711358","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-010-0985-4"},{"key":"bibr11-0300060517711358","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1097\/PAS.0b013e31824dd972","volume":"36","author":"Sukov WR","year":"2012","journal-title":"Am. 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