{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T16:45:00Z","timestamp":1784133900536,"version":"3.55.0"},"reference-count":22,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2017,7,31]],"date-time":"2017-07-31T00:00:00Z","timestamp":1501459200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2017,7,31]],"date-time":"2017-07-31T00:00:00Z","timestamp":1501459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2018,1]]},"abstract":"\n Objective<\/jats:title>\n \n To measure the rate of the A2063G mutation in the\n Mycoplasma pneumoniae<\/jats:italic>\n (\n M. pneumoniae<\/jats:italic>\n ) 23S rRNA domain V in children with pneumonia and to determine the correlation between radiographic findings and the presence of the A2063G mutation.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Patients who were hospitalized with a confirmed diagnosis of\n M. pneumoniae<\/jats:italic>\n pneumonia were enrolled in this study.\n M. pneumoniae<\/jats:italic>\n strains were collected for genotype analysis. Chest radiography was performed on all children prior to and following macrolide treatment. Clinical and imaging data were obtained.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Of 211 patients, 195 (92.42%) harboured\n M. pneumoniae<\/jats:italic>\n with the A2063G mutation. No significant differences were identified in inflammation score, chest radiography inflammation absorption grade before and after macrolide treatment, or pulmonary complications (atelectasis, hydrothorax, or pleuritis) prior to macrolide treatment when children were stratified based on the presence or absence of the A2063G mutation.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n A high proportion of children with pneumonia harboured strains of\n M. pneumoniae<\/jats:italic>\n with the A2063G mutation in the 23S rRNA domain V. However, no obvious chest radiographic features of\n M. pneumoniae<\/jats:italic>\n pneumonia were associated with the A2063G variant.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1177\/0300060517716312","type":"journal-article","created":{"date-parts":[[2017,8,1]],"date-time":"2017-08-01T00:47:43Z","timestamp":1501548463000},"page":"150-157","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":14,"title":["Mycoplasma pneumoniae<\/i>\n 23S rRNA A2063G mutation does not influence chest radiography features in children with pneumonia"],"prefix":"10.1177","volume":"46","author":[{"given":"Huan","family":"Deng","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine, Children\u2019s Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Rui","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Children\u2019s Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deyu","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Children\u2019s Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Children\u2019s Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2017,7,31]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1586\/14787210.6.4.509"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.17.4.697-728.2004"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01806-13"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-200X.2008.02622.x"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/MOP.0b013e328341579c"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-10-39"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.014191-0"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2567.2011.03408.x"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2000.01841.x"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.2174\/1568005054880109"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00048-13"},{"key":"e_1_3_5_13_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.49.6.2302-2306.2005"},{"key":"e_1_3_5_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.22851"},{"key":"e_1_3_5_15_2","first-page":"725","article-title":"Associations of radiological features in Mycoplasma pneumoniae pneumonia","volume":"10","author":"Guo Q","year":"2014","unstructured":"Guo Q, Li HY, Zhou YP, et al. Associations of radiological features in Mycoplasma pneumoniae pneumonia. Arch Med Sci 2014; 10: 725\u2013732.","journal-title":"Arch Med Sci"},{"key":"e_1_3_5_16_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.48.12.4624-4630.2004"},{"key":"e_1_3_5_17_2","unstructured":"National Center for Biotechnology Information U.S. National Library of Medicine. https:\/\/blast.ncbi.nlm.nih.gov\/Blast.cgi."},{"key":"e_1_3_5_18_2","first-page":"185","article-title":"Preliminary development and application of evaluation questionnaire of pneumonia inflammation (China)","volume":"11","author":"Yin R","year":"2012","unstructured":"Yin R, Li M, Xu H, et al. Preliminary development and application of evaluation questionnaire of pneumonia inflammation (China). Chinese Journal of Respiratory and Critical Care Medicine 2012; 11: 185\u2013187.","journal-title":"Chinese Journal of Respiratory and Critical Care Medicine"},{"key":"e_1_3_5_19_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.00695"},{"key":"e_1_3_5_20_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.73.5.2828-2834.2005"},{"key":"e_1_3_5_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2010.07092.x"},{"key":"e_1_3_5_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2011.05.031"},{"key":"e_1_3_5_23_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.02186-14"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300060517716312","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0300060517716312","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300060517716312","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:54:09Z","timestamp":1777460049000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0300060517716312"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7,31]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["10.1177\/0300060517716312"],"URL":"https:\/\/doi.org\/10.1177\/0300060517716312","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,7,31]]}}}