{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:40:05Z","timestamp":1777729205711,"version":"3.51.4"},"reference-count":20,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2018,1,14]],"date-time":"2018-01-14T00:00:00Z","timestamp":1515888000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:p>Abstracts<\/jats:p>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To assess how induction chemotherapy affects the quality-of-life (QoL) in patients with advanced tongue cancer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This prospective study included patients who were diagnosed with advanced tongue cancer. Each patient was asked to complete the University of Washington QoL (UW-QoL), version 4, questionnaire preoperatively and at 12 months after surgery. Patients were divided into two groups based on whether or not they received induction chemotherapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of the 192 patients included in the analysis, 145 patients had received induction chemotherapy. There were no significant differences regarding age, sex, tumour stage, node stage, flap reconstruction, tumour resection range and radiotherapy between the two groups. The mean total hospital cost was significantly higher in patients who underwent induction chemotherapy compared with those who did not (68\u00a0000 versus 44\u00a0000 Yuan Renminbi, respectively). The two groups had similar pre-treatment and post-treatment composite QoL scores and in the 12 individual domains.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Induction chemotherapy had a limited effect on postoperative QoL in patients with advanced tongue cancers, but it cost significantly more to administer.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0300060517721073","type":"journal-article","created":{"date-parts":[[2018,1,15]],"date-time":"2018-01-15T08:14:44Z","timestamp":1516004084000},"page":"1461-1466","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Effect of induction chemotherapy on the quality-of-life in patients with advanced stage tongue cancer by a prospective study"],"prefix":"10.1177","volume":"46","author":[{"given":"Tao","family":"Huang","sequence":"first","affiliation":[{"name":"Department of Breast Cancer, Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, Henan Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Breast Cancer, Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, Henan Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Stomatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanxia","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Stomatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,1,14]]},"reference":[{"key":"bibr1-0300060517721073","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2014.2054"},{"key":"bibr2-0300060517721073","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000000710"},{"key":"bibr3-0300060517721073","doi-asserted-by":"publisher","DOI":"10.1002\/hed.24739"},{"key":"bibr4-0300060517721073","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6605860"},{"key":"bibr5-0300060517721073","doi-asserted-by":"publisher","DOI":"10.2217\/fon-2016-0544"},{"key":"bibr6-0300060517721073","doi-asserted-by":"publisher","DOI":"10.21873\/anticanres.11276"},{"key":"bibr7-0300060517721073","doi-asserted-by":"publisher","DOI":"10.1186\/s40880-016-0157-4"},{"key":"bibr8-0300060517721073","unstructured":"The Union of International Cancer Control (UICC). TNM Classification of Malignant Tumours 8\n                      th\n                      Edition, http:\/\/www.uicc.org\/resources\/tnm (2016, accessed 4 September 2017)."},{"key":"bibr9-0300060517721073","unstructured":"University of Washington Quality of Life Questionnaire (UW-QOL v4). Guidance for scoring and presentation. http:\/\/www.headandneckcancer.co.uk\/File.ashx?id=10285 (2012, accessed 4 September 2017)."},{"key":"bibr10-0300060517721073","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2014.01.010"},{"key":"bibr11-0300060517721073","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2013.07.011"},{"key":"bibr12-0300060517721073","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000000443"},{"key":"bibr13-0300060517721073","doi-asserted-by":"publisher","DOI":"10.1002\/hed.23254"},{"key":"bibr14-0300060517721073","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2012.09.005"},{"key":"bibr15-0300060517721073","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdt461"},{"key":"bibr16-0300060517721073","doi-asserted-by":"publisher","DOI":"10.1159\/000065470"},{"key":"bibr17-0300060517721073","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20989"},{"key":"bibr18-0300060517721073","doi-asserted-by":"publisher","DOI":"10.1002\/hed.23635"},{"key":"bibr19-0300060517721073","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2012.04.004"},{"key":"bibr20-0300060517721073","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.134.10.1060"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300060517721073","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0300060517721073","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300060517721073","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:54:19Z","timestamp":1777460059000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0300060517721073"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1,14]]},"references-count":20,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,4]]}},"alternative-id":["10.1177\/0300060517721073"],"URL":"https:\/\/doi.org\/10.1177\/0300060517721073","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,1,14]]}}}