{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:03:06Z","timestamp":1777726986981,"version":"3.51.4"},"reference-count":35,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2017,9,20]],"date-time":"2017-09-20T00:00:00Z","timestamp":1505865600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study was performed to evaluate the efficacy and feasibility of percutaneous mechanical thrombectomy (PMT) combined with catheter-directed thrombolysis (CDT) in patients with acute pulmonary embolism (APE) and lower extremity deep venous thrombosis (LEDVT).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In total, 20 consecutive patients with APE and LEDVT were prospectively selected for PMT combined with CDT. Mechanical thrombus fragmentation and aspiration using a pigtail rotation catheter followed by CDT was performed in each patient. Details regarding the patients\u2019 clinical presentation and outcome, pulmonary status parameters (pulmonary arterial pressure, partial pressure of oxygen in arterial blood, Miller score, thigh and calf circumference, and shock index), and lower extremity parameters (thrombus-lysis grade and Villalta scale score) were recorded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>All 20 patients\u2019 clinical manifestations significantly improved. Both the clinical success rate and technical success rate were 100%. No major adverse events occurred during hospitalization. Four patients developed iliac vein compression syndrome and underwent stent implantation in the iliac vein. No pulmonary embolism recurred within 16.5\u00b16.8 months of follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The combination of PMT and CDT is a safe and effective treatment for APE and LEDVT with good short- and intermediate-term clinical outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0300060517729898","type":"journal-article","created":{"date-parts":[[2017,9,20]],"date-time":"2017-09-20T08:58:40Z","timestamp":1505897920000},"page":"836-851","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":17,"title":["Percutaneous mechanical thrombectomy combined with catheter-directed           thrombolysis in the treatment of acute pulmonary embolism and lower extremity deep venous           thrombosis: A novel one-stop endovascular strategy"],"prefix":"10.1177","volume":"46","author":[{"given":"Bing","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Vascular Surgery, The Affiliated Hospital of Qingdao\r          University, HuangDao District, Shandong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6449-4885","authenticated-orcid":false,"given":"MingYuan","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, Peking University People?s Hospital, West\r          District, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"LiHong","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, The Affiliated Hospital of Qingdao\r          University, HuangDao District, Shandong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JunWei","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, The Affiliated Hospital of Qingdao\r          University, HuangDao District, Shandong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiang","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, The Affiliated Hospital of Qingdao\r          University, HuangDao District, Shandong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"XueFei","family":"Jiao","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, The Affiliated Hospital of Qingdao\r          University, HuangDao District, Shandong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MingJin","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, The Affiliated Hospital of Qingdao\r          University, HuangDao District, Shandong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,9,20]]},"reference":[{"key":"bibr1-0300060517729898","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.93.12.2212"},{"key":"bibr2-0300060517729898","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa032274"},{"key":"bibr3-0300060517729898","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.164.1.17"},{"key":"bibr4-0300060517729898","doi-asserted-by":"publisher","DOI":"10.1583\/11-3674MR.1"},{"key":"bibr5-0300060517729898","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcad.2011.03.008"},{"key":"bibr6-0300060517729898","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-2299"},{"key":"bibr7-0300060517729898","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehu283"},{"key":"bibr8-0300060517729898","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.5763.681"},{"key":"bibr9-0300060517729898","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.113.005544"},{"key":"bibr10-0300060517729898","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.183.3.1830589"},{"key":"bibr11-0300060517729898","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.211.1.r99ap4739"},{"key":"bibr12-0300060517729898","doi-asserted-by":"publisher","DOI":"10.1007\/s00270-009-9591-x"},{"key":"bibr13-0300060517729898","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(00)00734-8"},{"key":"bibr14-0300060517729898","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2009.03294.x"},{"key":"bibr15-0300060517729898","unstructured":"Mattos MA,                  andSumner DS.           Direct noninvasive tests (duplex scan) for the evaluation of chronic venous obstruction           and valvular incompetence.\n                      Handbook of venous disorders 2nd ed New York,             NY\n                      . 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