{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:06:20Z","timestamp":1787018780301,"version":"build-2736575974"},"reference-count":55,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2018,4,24]],"date-time":"2018-04-24T00:00:00Z","timestamp":1524528000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>High-quality data indicating the advantages of preoperative Helicobacter pylori screening and eradication as well the clinical outcomes of patients with and without H. pylori after bariatric surgery are lacking.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In total, 96 morbidly obese patients with H. pylori preparing for bariatric surgery were retrospectively reviewed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 96 biopsy specimens, 73 (76%) were positive for H. pylori on initial Giemsa staining. These patients were treated with the standard 7-day antibiotic treatment protocol corrected by the individual patient\u2019s creatinine clearance rate and body mass index and received a 30% higher dose because of their H. pylori positivity. A linear correlation was found between the effective antibiotic dose and the BMI with a recurrence rate of only 2.1% (2\/96 patients). The preoperative percent estimated weight loss before surgery (17%) and in the first year of follow-up (68%\u201388%) was statistically equal between H. pylori-positive and -negative patients. Two early postoperative infectious complications and two postoperative surgical complications occurred in the preoperatively H. pylori-positive patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>A patient-tailored H. pylori eradication protocol prior to bariatric surgery is mandatory to improve the eradication rate and reduce the incidence of postoperative complications in mostly asymptomatic H. pylori-positive bariatric candidates.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0300060518769543","type":"journal-article","created":{"date-parts":[[2018,4,25]],"date-time":"2018-04-25T02:39:46Z","timestamp":1524623986000},"page":"2696-2707","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":16,"title":["The need for a patient-tailored\n                    <i>Helicobacter pylori<\/i>\n                    eradication protocol prior to bariatric surgery"],"prefix":"10.1177","volume":"46","author":[{"given":"Tadeja","family":"Pintar","sequence":"first","affiliation":[{"name":"University Medical Center Ljubljana, Abdominal Surgery Department, Zalo\u0161ka cesta, Ljubljana, Slovenia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niko","family":"Kaliterna","sequence":"additional","affiliation":[{"name":"Gimnazija Bezigrad, Periceva ul, Ljubljana, Slovenia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanja","family":"Carli","sequence":"additional","affiliation":[{"name":"Institute of Physiology, Faculty of Medicine, University of Ljubljana, Zalo\u0161ka cesta, Ljubljana, Slovenia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,4,24]]},"reference":[{"key":"bibr1-0300060518769543","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2012-302084"},{"key":"bibr2-0300060518769543","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(91)90644-Z"},{"key":"bibr3-0300060518769543","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(91)90644-Z"},{"key":"bibr4-0300060518769543","first-page":"265","volume":"96","author":"de la Riva S","year":"2004","journal-title":"Rev Esp Enfermedades Dig"},{"key":"bibr5-0300060518769543","first-page":"140","volume":"6","author":"Albawardi A","year":"2013","journal-title":"Int J Clin Exp Med"},{"key":"bibr6-0300060518769543","doi-asserted-by":"publisher","DOI":"10.1007\/s11695-013-1108-7"},{"key":"bibr7-0300060518769543","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i3.647"},{"key":"bibr8-0300060518769543","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-007-9285-x"},{"key":"bibr9-0300060518769543","doi-asserted-by":"publisher","DOI":"10.1381\/096089202321019594"},{"key":"bibr10-0300060518769543","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2012.60"},{"key":"bibr11-0300060518769543","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2010.06225.x"},{"key":"bibr12-0300060518769543","unstructured":"WHO. 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