{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T02:21:31Z","timestamp":1791685291886,"version":"4.3.4"},"reference-count":30,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2018,7,12]],"date-time":"2018-07-12T00:00:00Z","timestamp":1531353600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study was performed to identify risk factors for acute cellular rejection after liver transplantation (LT).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Consecutive LT recipients who underwent surgery in our institution from 2002 to 2015 were retrospectively evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In total, 176 patients were eligible for statistical analysis. During a mean observation period of 61.1\u2009\u00b1\u200936.3 months, 43 episodes of acute rejection were evident. Of these, 34 (79.0%) were responsive to methylprednisolone, 3 (7.0%) were treated by adjusting the dosage of immunosuppressive agents, and 6 (14.0%) were methylprednisolone-resistant and treated using anti-thymocyte globulin. Biliary complications (odds ratio [OR]\u2009=\u20094.89, 95% confidence interval [CI]\u2009=\u20092.00\u201311.98); donor-negative, recipient-positive CMV mismatch (OR\u2009=\u20099.88, 95% CI\u2009=\u20091.18\u201382.36); sex mismatch (OR\u2009=\u20093.16, 95% CI\u2009=\u20091.31\u20138.10); and sex mismatch with a female donor (OR\u2009=\u20093.00, 95% CI\u2009=\u20091.10\u20137.58) were identified as significant risk factors for acute graft rejection after LT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In patients who develop acute cellular rejection after LT, biliary complications should be evaluated as a potential cause. Most acute rejections after LT respond to bolus corticosteroid therapy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0300060518785543","type":"journal-article","created":{"date-parts":[[2018,7,12]],"date-time":"2018-07-12T03:07:36Z","timestamp":1531364856000},"page":"3979-3990","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":73,"title":["Acute allograft rejection in liver transplant recipients: Incidence, risk factors, treatment success, and impact on graft failure"],"prefix":"10.1177","volume":"46","author":[{"given":"Nurettin","family":"Dogan","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Hepatology, University Hospital Muenster, Muenster, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"H\u00fcsing-Kabar","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, University Hospital Muenster, Muenster, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hartmut H.","family":"Schmidt","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, University Hospital Muenster, Muenster, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vito R.","family":"Cicinnati","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, University Hospital Muenster, Muenster, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanne","family":"Beckebaum","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, University Hospital Muenster, Muenster, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iyad","family":"Kabar","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, University Hospital Muenster, Muenster, 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