{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T14:16:30Z","timestamp":1782828990080,"version":"3.54.5"},"reference-count":17,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2018,8,28]],"date-time":"2018-08-28T00:00:00Z","timestamp":1535414400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study was performed to discuss the characteristics, diagnosis, and treatment of primary prostatic extragastrointestinal stromal tumor (EGIST).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The case history data of a patient with an EGIST were analyzed and discussed with a literature review.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The patient was diagnosed with a pelvic tumor, possibly malignant. We ascertained the diagnosis by exploratory surgery and pathological biopsy. The tumor was present in the prostate and infiltrated and pressed against the anterior rectal wall. Pathological biopsy showed that the tumor comprised spindle cells, which were also present at the junction of the tumor and prostate tissue. Immunohistochemically, the tumor cells were positive for CD117, DOG-1, CD34, and smooth muscle actin and negative for S100 and desmin; Ki-67LI was about 10%. These results support the diagnosis of primary prostatic EGIST.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The rarity and nonspecific clinical manifestation of prostatic EGIST facilitate misdiagnosis. Diagnosis mainly depends on imaging examination and characteristic histopathological and immunohistochemical features, and GIST must be excluded. Surgery is the main treatment method, and imatinib is suggested for unresectable and malignant EGISTs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0300060518791677","type":"journal-article","created":{"date-parts":[[2018,8,28]],"date-time":"2018-08-28T08:06:31Z","timestamp":1535443591000},"page":"4343-4349","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["Primary prostatic extragastrointestinal stromal tumor: a case report and literature review"],"prefix":"10.1177","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4813-107X","authenticated-orcid":false,"given":"Yong-hao","family":"You","sequence":"first","affiliation":[{"name":"Department of Surgery, the First Clinical Medical College of Yangtze University, Jingzhou, Hubei Province, China"},{"name":"Department of Surgery, the First Affiliated Hospital of Yangtze University, Jingzhou, Hubei Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Urology, Huangpi District People\u2019s Hospital, Wuhan, Hubei Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,8,28]]},"reference":[{"key":"bibr1-0300060518791677","doi-asserted-by":"publisher","DOI":"10.5001\/omj.2014.34"},{"key":"bibr2-0300060518791677","first-page":"43","volume":"1","author":"Tornillo L.","year":"2014","journal-title":"Front Med (Lausanne)"},{"key":"bibr3-0300060518791677","first-page":"83","volume":"5","author":"Li Wei","year":"2014","journal-title":". 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