{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:12:36Z","timestamp":1777727556520,"version":"3.51.4"},"reference-count":15,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2018,11,22]],"date-time":"2018-11-22T00:00:00Z","timestamp":1542844800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Key Clinical Specialty Discipline Construction of Fujian ,P.R.C","award":["[2015] no. 593"],"award-info":[{"award-number":["[2015] no. 593"]}]},{"name":"Fujian Science and Technology Key Project","award":["2014Y005"],"award-info":[{"award-number":["2014Y005"]}]},{"name":"National Health and Family Planning Commission Science Foundation","award":["WKJ-FJ-09"],"award-info":[{"award-number":["WKJ-FJ-09"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To investigate the expression of \u03b2-catenin in chorionic villi, and to explore its roles in placenta accreta and placenta previa.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We compared \u03b2-catenin expression in the control group, placenta accreta group (lesion area and normal zones), and placenta previa group (placental central and placental edge zones) by immunohistochemistry, Western blotting, and RT-PCR techniques.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Compared with the normal group, the placenta accreta group had a longer length of stay, greater bleeding volume, and lower newborn birth weight. Further, the expression of \u03b2-catenin was lower in both placenta previa and placenta accreta groups than in the control group, as measured by immunohistochemistry. Compared with the control group, expression of \u03b2-catenin was significantly lower in the placenta previa and placenta accreta groups by Western blotting and RT-PCR. Importantly, the level of placental \u03b2-catenin was significantly different when compared between the lesion and normal zones of placenta.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The expression of \u03b2-catenin in placenta accreta might play an important role in the regulation of placental cell invasion; low expression of \u03b2-catenin in placenta accreta might be responsible for excessive trophoblastic invasion.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0300060518799265","type":"journal-article","created":{"date-parts":[[2018,11,22]],"date-time":"2018-11-22T06:26:57Z","timestamp":1542868017000},"page":"206-214","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Expression of \u03b2-catenin in human trophoblast and its role in placenta accreta and placenta previa"],"prefix":"10.1177","volume":"47","author":[{"given":"Qing","family":"Han","sequence":"first","affiliation":[{"name":"Department of Obstetrics, Fujian Provincial Maternity and Children\u2019s Hospital, Affiliated Hospital of Fujian Medical University, Fujian, Fuzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lianghui","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Fujian Provincial Maternity and Children\u2019s Hospital, Affiliated Hospital of Fujian Medical University, Fujian, Fuzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhaodong","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Fujian Provincial Maternity and Children\u2019s Hospital, Affiliated Hospital of Fujian Medical University, Fujian, Fuzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinying","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Fujian Provincial Maternity and Children\u2019s Hospital, Affiliated Hospital of Fujian Medical University, Fujian, Fuzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rongxin","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Fujian Provincial Maternity and Children\u2019s Hospital, Affiliated Hospital of Fujian Medical University, Fujian, Fuzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianying","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Fujian Provincial Maternity and Children\u2019s Hospital, Affiliated Hospital of Fujian Medical University, Fujian, Fuzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,11,22]]},"reference":[{"key":"bibr1-0300060518799265","doi-asserted-by":"publisher","DOI":"10.1097\/PGP.0000000000000233"},{"key":"bibr2-0300060518799265","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/567305"},{"key":"bibr3-0300060518799265","first-page":"223","volume":"3","author":"Cheng JC","year":"2015","journal-title":"Chinese J Perinatal 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