{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T15:53:34Z","timestamp":1785340414221,"version":"3.55.0"},"reference-count":32,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81770876; 81270011; 81472125"],"award-info":[{"award-number":["81770876; 81270011; 81472125"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"the Shanghai Municipal Health and Family Planning Commission Fund Project","award":["201640057"],"award-info":[{"award-number":["201640057"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to evaluate the ef\ufb01cacy of beraprost sodium (BPS) or clopidogrel (CL) using vascular thromboembolic events (VTEs) of arteriovenous fistula as a primary endpoint in patients with end-stage renal disease (ESRD) undergoing arteriovenous fistula surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We performed a multicentre, retrospective cohort study from August 2012 to August 2016. We studied patients with ESRD who underwent arteriovenous fistula surgery and received peroral administration of 40 \u00b5g BPS, three times per day, for 1 month, or 75 mg CL (initial dose of 300 mg), one time per day, for 1 month. The time to first on-study VTE was the primary endpoint.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The BPS-treated cohort had a significantly delayed time to first VTE compared with the CL-treated cohort (hazard ratio 0.33, 95% confidence interval 0.18\u20130.56). An increased incidence of VTEs was detected in the 1-month follow-up, with rates of 2.4% and 8.7% for BPS and CL, respectively. This difference persisted over time, with rates of 8.0% and 18.1% at the final follow-up, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>CL-treated patients with ESRD have a greater risk of VTEs compared with BPS-treated patients. CL-treated patients also tend to experience a VTE within the first month after cessation of oral administration.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0300060518800517","type":"journal-article","created":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T07:26:38Z","timestamp":1538378798000},"page":"252-264","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Beraprost sodium versus clopidogrel for preventing vascular thromboembolic events of arteriovenous fistula in uraemic patients: a retrospective study with a mean 3-year follow-up"],"prefix":"10.1177","volume":"47","author":[{"given":"Ziming","family":"Wan","sequence":"first","affiliation":[{"name":"Department of Nephrology, The First Affiliated Hospital of Chongqing Medical University, Yuzhong District, Chongqing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Zhu","sequence":"additional","affiliation":[{"name":"Radiology Department, The First Affiliated Hospital, Sun Yat-sen University, Yuexiu District, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruikun","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, The First Affiliated Hospital, Sun Yat-sen University, Yuexiu District, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongjian","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Thoracic surgery, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Jianghan District, Wuhan, Hubei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Physical Examination, The First Affiliated Hospital, Sun Yat-sen University, Yuexiu District, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Cao","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Jianghan District, Wuhan, Hubei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjing","family":"Yan","sequence":"additional","affiliation":[{"name":"The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Jianghan District, Wuhan, Hubei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Jianghan District, Wuhan, Hubei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Neurology, The Affiliated Hospital of Hebei University, Baoding, Hebei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingdong","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Jinshan Hospital, Fudan University, Jinshan District, Shanghai City, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keke","family":"Gui","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Jinshan Hospital, Fudan University, Jinshan District, Shanghai City, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Xiong","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Jinshan Hospital, Fudan University, Jinshan District, Shanghai City, 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