{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:18:09Z","timestamp":1777727889642,"version":"3.51.4"},"reference-count":44,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2019,1,13]],"date-time":"2019-01-13T00:00:00Z","timestamp":1547337600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2019,1,13]],"date-time":"2019-01-13T00:00:00Z","timestamp":1547337600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To examine the safety and effectiveness of individualized treatment strategies that include three principles (security, top-down and priority) for patients with obstructive sleep apnoea hypopnea syndrome (OSAHS) and multilevel obstruction who decline therapy with continuous positive airway pressure (CPAP).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients with OSAHS and upper airway obstruction who were diagnosed with multilevel obstruction were included in this retrospective study. Patients were evaluated for the degree of obstruction in each level. Three principles were followed in planning the appropriate intervention level and measures to reduce perioperative risks. Polysomnography indices and Epworth sleepiness scores were used to evaluate the efficacy of surgery and improvement in patients\u2019 sleepiness at \u22653 months post-surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 51 patients with OSAHS and multilevel obstruction, three were treated with CPAP, 41 were treated with nasopharyngeal surgery, and seven were treated with oropharyngeal surgery. No severe complications were reported. Following surgery, apnoea hypopnea index and Epworth sleepiness scores were significantly reduced, and the lowest oxygen saturation level was significantly increased.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The three-principle strategy was safe and effective in planning surgical treatments for patients with OSAHS and multilevel obstruction.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0300060518822209","type":"journal-article","created":{"date-parts":[[2019,1,14]],"date-time":"2019-01-14T01:07:42Z","timestamp":1547428062000},"page":"1533-1543","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Strategies in the clinical diagnosis and surgical treatment of OSAHS with multilevel obstruction"],"prefix":"10.1177","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8194-4980","authenticated-orcid":false,"given":"Ben-Gang","family":"Peng","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology, Jishuitan Hospital, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"You-Qing","family":"Lai","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Jishuitan Hospital, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui-Jia","family":"Lei","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Jishuitan Hospital, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ning","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Jishuitan Hospital, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Jishuitan Hospital, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,1,13]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0187032"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0184293"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsmc.2017.07.004"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11325-011-0542-9"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2010.10.003"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.6892"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004050000278"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1159\/000089836"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.27497"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.2172"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2003.09.016"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199906000-00022"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1177\/0003489418778302"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200403000-00013"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215111003082"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.21037\/atm.2016.02.11"},{"key":"e_1_3_2_18_2","first-page":"539","article-title":"The study on AHI, LSaO2 and ET-1 in patients with obstructive sleep apnea-hypopnea syndrome after H-UPPP","volume":"26","author":"Wu X","year":"2012","unstructured":"Wu X, Yu Y, Hu D. The study on AHI, LSaO2 and ET-1 in patients with obstructive sleep apnea-hypopnea syndrome after H-UPPP. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2012; 26: 539\u2013541 [In Chinese].","journal-title":"Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1159\/000327176"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00019.2010"},{"key":"e_1_3_2_21_2","first-page":"109","article-title":"Multilevel obstructive sleep apnea surgery","volume":"80","author":"Lin HC","year":"2017","unstructured":"Lin HC, Weaver EM, Lin HS, et\u00a0al. Multilevel obstructive sleep apnea surgery. Adv Otorhinolaryngol 2017; 80: 109\u2013115.","journal-title":"Adv Otorhinolaryngol"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00050208"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2006.01.015"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11596-011-0392-5"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201601-0088OC"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.163.5.2007013"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12265-010-9238-y"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.7326\/L14-5005-2"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.134.4.429"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.3109\/00016489.2011.615760"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2007.04.007"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0000000000000407"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000004883"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.1991.tb01050.x"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2007.04.009"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1159\/000087390"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2005.03.061"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1111\/coa.12925"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199108000-00001"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.2310\/7070.2003.40315"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2008.11.003"},{"key":"e_1_3_2_42_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2014.06.015"},{"key":"e_1_3_2_43_2","doi-asserted-by":"publisher","DOI":"10.21037\/atm.2016.02.15"},{"key":"e_1_3_2_44_2","doi-asserted-by":"publisher","DOI":"10.21037\/atm.2016.03.35"},{"key":"e_1_3_2_45_2","doi-asserted-by":"publisher","DOI":"10.21037\/atm.2016.08.57"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300060518822209","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0300060518822209","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300060518822209","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:50:42Z","timestamp":1777459842000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0300060518822209"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,13]]},"references-count":44,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,4]]}},"alternative-id":["10.1177\/0300060518822209"],"URL":"https:\/\/doi.org\/10.1177\/0300060518822209","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1,13]]}}}