{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T20:53:29Z","timestamp":1778705609171,"version":"3.51.4"},"reference-count":27,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2019,2,20]],"date-time":"2019-02-20T00:00:00Z","timestamp":1550620800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The objectives of this retrospective review were to: (a) determine the prevalence of resistant Gram-negative bacteraemia among hospitalized patients; (b) evaluate antibiotic use; (c) determine the time taken for Gram staining to final species identification.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>For this retrospective study, information was extracted from patients\u2019 electronic medical records. Eligible patients had been admitted to a 300-bed tertiary care hospital in Tucson, Arizona from October 2015 to October 2016, were over 18 years of age and had a positive blood culture for Gram-negative bacteraemia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In total, 84 patients with Gram-negative bacteraemia were identified; urinary tract infection was the most common source of infection (71%). ESBL-producing microorganisms were isolated from five (6%) patients and no MDR pathogens were identified. The, median time to Gram stain was 20.5 hours and the median time to final identification was 54.5 hours. Delayed de-escalation of broad-spectrum antibiotics (i.e., &gt;24 hours after final culture) occurred in 25% patients with a median length of hospital stay of 118 hours (range: 56\u2013552 hours) compared with a median length of hospital stay of 89 hours (range: 5\u2013334 hours) in the early de-escalation group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The prevalence of bacteraemia due to resistant Gram-negative microorganisms is low (6%) in this institution. However, there may be room for improvement in the antimicrobial stewardship program with regard to rapid diagnostic testing.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0300060519829987","type":"journal-article","created":{"date-parts":[[2019,2,20]],"date-time":"2019-02-20T16:43:27Z","timestamp":1550681007000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["The prevalence of resistant Gram-negative bacteraemia among hospitalized patients in Tucson, Arizona over a 12-month period; A retrospective single center study"],"prefix":"10.1177","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3727-7543","authenticated-orcid":false,"given":"Abdulaziz Saleh","family":"Almulhim","sequence":"first","affiliation":[{"name":"King Faisal University, College of Clinical Pharmacy, Saudi Arabia; The University of Arizona, College of Pharmacy, Tucson, Arizona, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmad","family":"Alamer","sequence":"additional","affiliation":[{"name":"Prince Sattam Bin Abdulaziz University, College of Pharmacy, Alkharj, Saudi Arabia; The University of Arizona, College of Pharmacy, Tucson, Arizona, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,2,20]]},"reference":[{"key":"bibr1-0300060519829987","unstructured":"Centers for Disease Control and Prevention (CDC). 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