{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T14:10:41Z","timestamp":1784556641216,"version":"3.55.0"},"reference-count":29,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2019,4,2]],"date-time":"2019-04-02T00:00:00Z","timestamp":1554163200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Both compound vitamin B mixtures and GeneTime\u00ae have been used in treatment of oral inflammation. This study aimed to assess the therapeutic effects of a compound vitamin B mixture combined with GeneTime\u00ae on radiation-induced oral mucositis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 100 patients with radiation-induced oral mucositis were randomly divided into a control group (vitamin B alone; n\u2009=\u200950 patients) and an observation group (vitamin B plus GeneTime\u00ae, n\u2009=\u200950 patients). Clinical outcomes were compared between the two groups for the following 3 weeks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The observation group had a significantly greater number of grade 0\u2013I patients and significantly fewer grade II\u2013IV patients than the control group. Among patients in the observation group, a significantly greater number of ulcers healed within 1\u20132 weeks, compared with those in patients in the control group. Significantly fewer ulcers healed among patients in the observation group at 3 weeks; notably, there were fewer ulcers to heal in the observation group, compared with the control group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Use of a compound vitamin B mixture combined with GeneTime\u00ae exerted obvious therapeutic effects on radiation-induced oral mucositis and markedly shortened ulcer healing time. Therefore, this strategy may be useful in clinical applications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0300060519831171","type":"journal-article","created":{"date-parts":[[2019,4,2]],"date-time":"2019-04-02T08:35:43Z","timestamp":1554194143000},"page":"2126-2134","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Effects of a compound vitamin B mixture in combination with GeneTime\u00ae on radiation-induced oral mucositis"],"prefix":"10.1177","volume":"47","author":[{"given":"Hui","family":"Sun","sequence":"first","affiliation":[{"name":"Department of Stomatology, Chinese PLA General Hospital, Beijing, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoshuai","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Shandong Weifang Yi Du Central Hospital, Weifang, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Stomatology, Chinese PLA General Hospital, Beijing, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8768-2846","authenticated-orcid":false,"given":"Tao","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Stomatology, Chinese PLA General Hospital, Beijing, P. R. 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