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Cardiovascular events induced by thalidomide have been reported in patients with multiple myeloma, amyotrophic lateral sclerosis, and transfusion-dependent refractory anemia. We report here an extremely rare case of sinus bradycardia induced by thalidomide in an adult patient with CD. This patient\u2019s heart rate converted back to a normal sinus rhythm after withdrawal of thalidomide, but recurred after restarting of thalidomide. Cardiac toxicity should be closely monitored when using thalidomide in patients with CD.<\/jats:p>","DOI":"10.1177\/0300060519833293","type":"journal-article","created":{"date-parts":[[2019,3,5]],"date-time":"2019-03-05T04:45:33Z","timestamp":1551761133000},"page":"2228-2233","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Thalidomide-induced sinus bradycardia in Crohn\u2019s disease: case report and literature review"],"prefix":"10.1177","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6021-4447","authenticated-orcid":false,"given":"Menghui","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Cardiology, The First Affiliated Hospital, Sun Yet-sen University, Guangzhou, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoqing","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, 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