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The superficial high-intensity area on OCT presumably corresponded with the bright spots on CAS. The high-intensity superficial regions were thought to represent an iopromide\/paclitaxel mixture. The present serial observation demonstrated that the eluted drugs remained for at least 2 months but disappeared within 6 months. At the site where we observed the drugs, neointimal growth was successfully inhibited and stabilized at the 6-month follow-up. The association of eluted drugs after DCB angioplasty with consequent neointimal growth is of scientific interest. Further prospective imaging studies with a large sample size are warranted to clarify this association.<\/jats:p>","DOI":"10.1177\/0300060519837445","type":"journal-article","created":{"date-parts":[[2019,4,2]],"date-time":"2019-04-02T08:35:43Z","timestamp":1554194143000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Serial optical coherence tomography and angioscopic assessments of 10-year in-stent restenosis of Cypher sirolimus-eluting stent treated with drug-coated balloon angioplasty"],"prefix":"10.1177","volume":"48","author":[{"given":"Satoshi","family":"Suzuki","sequence":"first","affiliation":[{"name":"Department of Cardiology, Osaka Police Hospital, Osaka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shimpei","family":"Nakatani","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Osaka Police Hospital, Osaka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7564-2978","authenticated-orcid":false,"given":"Yohei","family":"Sotomi","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Osaka Police Hospital, Osaka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ichiro","family":"Shiojima","sequence":"additional","affiliation":[{"name":"Department of Medicine II, Kansai Medical University, Hirakata, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasushi","family":"Sakata","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Osaka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiharu","family":"Higuchi","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Osaka Police Hospital, Osaka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,4,2]]},"reference":[{"key":"bibr1-0300060519837445","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2014.07.224"},{"key":"bibr2-0300060519837445","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2014.11.016"},{"key":"bibr3-0300060519837445","author":"Sotomi Y","year":"2018","journal-title":"EuroIntervention"},{"key":"bibr4-0300060519837445","doi-asserted-by":"publisher","DOI":"10.1536\/ihj.16-277"},{"key":"bibr5-0300060519837445","doi-asserted-by":"publisher","DOI":"10.1007\/s00270-016-1346-x"},{"key":"bibr6-0300060519837445","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2017.10.012"},{"key":"bibr7-0300060519837445","doi-asserted-by":"crossref","first-page":"678","DOI":"10.4244\/EIJ-D-17-00884","volume":"14","author":"Sotomi Y","year":"2018","journal-title":"EuroIntervention"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300060519837445","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0300060519837445","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300060519837445","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:51:09Z","timestamp":1777459869000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0300060519837445"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,2]]},"references-count":7,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1]]}},"alternative-id":["10.1177\/0300060519837445"],"URL":"https:\/\/doi.org\/10.1177\/0300060519837445","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4,2]]},"article-number":"0300060519837445"}}