{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T01:23:28Z","timestamp":1783214608281,"version":"3.54.6"},"reference-count":17,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2019,3,28]],"date-time":"2019-03-28T00:00:00Z","timestamp":1553731200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"the Foundation of lanzhou science grant","award":["2017-4-56"],"award-info":[{"award-number":["2017-4-56"]}]},{"name":"the Foundation of Gansu natural science grant","award":["18JR3RA340"],"award-info":[{"award-number":["18JR3RA340"]}]},{"name":"the Foundation of The Frist Hospital of Lanzhou University","award":["2017-01"],"award-info":[{"award-number":["2017-01"]}]},{"name":"the Foundation of The Frist Hospital of Lanzhou University","award":["2017-13"],"award-info":[{"award-number":["2017-13"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:p>Premature ovarian insufficiency is characterized by reduced ovarian function in a young woman, resulting in an earlier menopause compared with women with normal ovarian function. It is a term that reflects the variable nature of the condition and is substantially less emotive than the formerly used \u2018premature ovarian failure\u2019, which suggested a single event in time. Tripterygium glycosides can damage ovarian function and cause infertility. This case report describes a 33-year-old female patient (gravida 0, parity 0) who presented with premature ovarian insufficiency after being treated with tripterygium glycosides for nephrotic syndrome. The woman received oestrogen-progestin replacement therapy (Femoston) and ovulation induction, which resulted in a successful pregnancy. The patient delivered a healthy baby girl. This case demonstrates that it is possible for a woman with tripterygium glycoside-induced premature ovarian insufficiency to become pregnant with the correct therapy.<\/jats:p>","DOI":"10.1177\/0300060519837834","type":"journal-article","created":{"date-parts":[[2019,3,29]],"date-time":"2019-03-29T00:15:23Z","timestamp":1553818523000},"page":"2274-2279","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Successful pregnancy with tripterygium glycoside-induced premature ovarian insufficiency: a case report"],"prefix":"10.1177","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1079-3652","authenticated-orcid":false,"given":"Yuan","family":"Yang","sequence":"first","affiliation":[{"name":"Key Laboratory for Reproductive Medicine and Embryology, The Reproductive Medicine Special Hospital of the First Hospital of Lanzhou University, Lanzhou, Gansu Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Ling","family":"Ma","sequence":"additional","affiliation":[{"name":"Key Laboratory for Reproductive Medicine and Embryology, The Reproductive Medicine Special Hospital of the First Hospital of Lanzhou University, Lanzhou, Gansu Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue-Hong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Key Laboratory for Reproductive Medicine and Embryology, The Reproductive Medicine Special Hospital of the First Hospital of Lanzhou University, Lanzhou, Gansu Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,3,28]]},"reference":[{"key":"bibr1-0300060519837834","doi-asserted-by":"publisher","DOI":"10.3109\/13697137.2015.1020484"},{"key":"bibr2-0300060519837834","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2010.04.011"},{"key":"bibr3-0300060519837834","doi-asserted-by":"publisher","DOI":"10.3109\/13697137.2012.700846"},{"key":"bibr4-0300060519837834","doi-asserted-by":"publisher","DOI":"10.1007\/s40618-016-0467-z"},{"key":"bibr5-0300060519837834","first-page":"144","volume":"7","author":"Chen XY","year":"2014","journal-title":"Int J Clin Exp Pathol"},{"key":"bibr6-0300060519837834","first-page":"10727","volume":"9","author":"Ma M","year":"2016","journal-title":"Int J Clin Exp Med"},{"key":"bibr7-0300060519837834","first-page":"54","volume":"5","author":"Ebrahimi M","year":"2011","journal-title":"Int J Fertil Steril"},{"key":"bibr8-0300060519837834","doi-asserted-by":"publisher","DOI":"10.1186\/s12882-015-0199-x"},{"key":"bibr9-0300060519837834","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2011.08.077"},{"key":"bibr10-0300060519837834","doi-asserted-by":"publisher","DOI":"10.1258\/mi.2010.010014"},{"key":"bibr11-0300060519837834","first-page":"8855","volume":"7","author":"Ma M","year":"2014","journal-title":"Int J Clin Exp Pathol"},{"key":"bibr12-0300060519837834","first-page":"1580","volume":"9","author":"Ma M","year":"2017","journal-title":"Am J Transl Res"},{"key":"bibr13-0300060519837834","doi-asserted-by":"publisher","DOI":"10.3109\/09513590.2012.665104"},{"key":"bibr14-0300060519837834","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2015-4063"},{"key":"bibr15-0300060519837834","doi-asserted-by":"publisher","DOI":"10.1097\/GME.0000000000000195"},{"key":"bibr16-0300060519837834","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0108343"},{"key":"bibr17-0300060519837834","doi-asserted-by":"publisher","DOI":"10.14423\/SMJ.0000000000000611"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300060519837834","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0300060519837834","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300060519837834","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:51:09Z","timestamp":1777459869000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0300060519837834"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3,28]]},"references-count":17,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,5]]}},"alternative-id":["10.1177\/0300060519837834"],"URL":"https:\/\/doi.org\/10.1177\/0300060519837834","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,3,28]]}}}