{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T14:09:59Z","timestamp":1777990199308,"version":"3.51.4"},"reference-count":16,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2019,4,16]],"date-time":"2019-04-16T00:00:00Z","timestamp":1555372800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:p>Beh\u00e7et\u2019s syndrome (BS) is an idiopathic, chronic, relapsing, multisystem, vascular-inflammatory disease. Neuro-Beh\u00e7et\u2019s syndrome (NBS) is a subtype of BS that mainly involves the central nervous system. Because of the heterogeneous involvement of NBS and the limited yearly numbers of new cases of NBS, estimating its course, prognosis, and treatment effect is difficult. Therefore, the efficacy of treatment for any form of NBS is unclear. We experienced a male patient with NBS and severe right uveitis. He received high-dose intravenous methylprednisolone (1000 mg\/day) pulse therapy for 3 days. Intravenous injection of cyclophosphamide (400 mg, twice a day) and oral administration of prednisone (40 mg in the morning, 20 mg in the evening) were applied. Uveitis was treated with retrobulbar injection of triamcinolone acetonide (40 mg per week). The patient\u2019s response was rapid with improved symptoms and signs. The therapeutic regimen of patients with BS has greatly advanced, leading to evidence-based guidelines. Methylprednisolone pulse therapy is important in treatment of BS. Novel therapeutic options are currently being examined to improve the prognosis of BS. These efforts will undoubtedly shed new light on this complex syndrome.<\/jats:p>","DOI":"10.1177\/0300060519839522","type":"journal-article","created":{"date-parts":[[2019,4,17]],"date-time":"2019-04-17T00:20:32Z","timestamp":1555460432000},"page":"2694-2701","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Neuro-Beh\u00e7et\u2019s syndrome with a severe ocular lesion"],"prefix":"10.1177","volume":"47","author":[{"given":"Dan","family":"Han","sequence":"first","affiliation":[{"name":"Department of Cardiology, The First Affiliated Hospital of Xi\u2019an Jiaotong University, Xi\u2019an, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, The First Affiliated Hospital of Xi\u2019an Jiaotong University, Xi\u2019an, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peng","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Cardiology, The First Affiliated Hospital of Xi\u2019an Jiaotong University, Xi\u2019an, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guogang","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Neurology, The First Affiliated Hospital of Xi\u2019an Jiaotong University, Xi\u2019an, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenfeng","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Neurology, The First Affiliated Hospital of Xi\u2019an Jiaotong University, Xi\u2019an, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,4,16]]},"reference":[{"key":"bibr1-0300060519839522","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-7020-4088-7.00110-3"},{"key":"bibr2-0300060519839522","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2006.01863.x"},{"key":"bibr3-0300060519839522","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.1994.tb00559.x"},{"key":"bibr4-0300060519839522","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(09)70015-8"},{"key":"bibr5-0300060519839522","first-page":"1015","volume":"20","author":"Kocer N","year":"1999","journal-title":"AJNR Am J Neuroradiol"},{"key":"bibr6-0300060519839522","first-page":"1078","volume":"335","author":"Criteria for diagnosis of Beh\u00e7et\u2019s disease","year":"1990","journal-title":"Lancet"},{"key":"bibr7-0300060519839522","doi-asserted-by":"publisher","DOI":"10.1007\/s004150170242"},{"key":"bibr8-0300060519839522","doi-asserted-by":"publisher","DOI":"10.1002\/art.27568"},{"key":"bibr9-0300060519839522","doi-asserted-by":"publisher","DOI":"10.1590\/abd1806-4841.20177359"},{"key":"bibr10-0300060519839522","doi-asserted-by":"publisher","DOI":"10.1097\/BOR.0000000000000562"},{"key":"bibr11-0300060519839522","first-page":"3","volume":"35","author":"Hatemi G","year":"2017","journal-title":"Clin Exp Rheumatol"},{"key":"bibr12-0300060519839522","doi-asserted-by":"publisher","DOI":"10.1007\/s11910-018-0843-5"},{"key":"bibr13-0300060519839522","doi-asserted-by":"publisher","DOI":"10.1111\/1756-185X.12248"},{"key":"bibr14-0300060519839522","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/122.11.2171"},{"key":"bibr15-0300060519839522","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-018-4193-z"},{"key":"bibr16-0300060519839522","doi-asserted-by":"publisher","DOI":"10.1186\/s13256-017-1261-z"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300060519839522","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0300060519839522","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300060519839522","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:51:11Z","timestamp":1777459871000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0300060519839522"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,16]]},"references-count":16,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["10.1177\/0300060519839522"],"URL":"https:\/\/doi.org\/10.1177\/0300060519839522","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4,16]]}}}