{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:22:31Z","timestamp":1777728151002,"version":"3.51.4"},"reference-count":16,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2019,5,13]],"date-time":"2019-05-13T00:00:00Z","timestamp":1557705600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:p>Nanophthalmos is a developmental ocular malformation that has been associated with high risks of uveal effusion syndrome and exudative retinal detachment (ERD). A variety of surgical procedures and systemic\/topical steroids have been described as effective for treatment of ERD. However, the possibility of side effects should be considered. Here, we describe a patient with nanophthalmos who was treated for recurrent ERD during long-term follow-up, and we discuss non-surgical treatment options that are available in such cases. A 43-year-old woman with bilateral nanophthalmos exhibited ERD in her right eye for one month. After partial thickness sclerectomy with central sclerostomy, the retina was completely reattached. However, ERD recurred 3 years later. The patient refused surgery; therefore, we employed conservative treatment of topical nonsteroidal anti-inflammatory drugs (NSAIDs) and observation. One month later, the retina was completely reattached. To the best of our knowledge, no previous report has described resolution of recurrent ERD in a patient with nanophthalmos using NSAIDs during long-term follow-up after successful surgical treatment. Our success using this approach suggests that it could be used as alternative treatment for ERD in patients with nanophthalmos before application of further treatments.<\/jats:p>","DOI":"10.1177\/0300060519847376","type":"journal-article","created":{"date-parts":[[2019,5,13]],"date-time":"2019-05-13T07:05:05Z","timestamp":1557731105000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Unusual rapid resolution of postsclerectomy exudative retinal detachment with topical NSAIDs therapy in a case of nanophthalmos"],"prefix":"10.1177","volume":"48","author":[{"given":"Boding","family":"Tong","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, The Second Xiangya Hospital, Central South University, Changsha, Hunan Province, China"},{"name":"Hunan Clinical Research Center of Ophthalmic Disease, Changsha, Hunan Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5453-3927","authenticated-orcid":false,"given":"Chao","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Pathology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0426-4156","authenticated-orcid":false,"given":"Xin","family":"Qi","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, The Second Xiangya Hospital, Central South University, Changsha, Hunan Province, China"},{"name":"Hunan Clinical Research Center of Ophthalmic Disease, Changsha, Hunan Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,5,13]]},"reference":[{"key":"bibr1-0300060519847376","doi-asserted-by":"publisher","DOI":"10.1038\/ejhg.2015.155"},{"key":"bibr2-0300060519847376","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2013-303465"},{"key":"bibr3-0300060519847376","first-page":"1017","volume":"21","author":"Khorram D","year":"2015","journal-title":"Mol Vis"},{"key":"bibr4-0300060519847376","first-page":"1069","volume":"49","author":"Xiao H","year":"2013","journal-title":"Zhonghua Yan Ke Za Zhi"},{"key":"bibr5-0300060519847376","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0420.1998.760421.x"},{"key":"bibr6-0300060519847376","doi-asserted-by":"publisher","DOI":"10.3341\/kjo.2013.27.4.294"},{"key":"bibr7-0300060519847376","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1097\/ICB.0b013e318297f6c1","volume":"7","author":"Abell RG","year":"2013","journal-title":"Retin Cases Brief Rep"},{"key":"bibr8-0300060519847376","doi-asserted-by":"publisher","DOI":"10.5005\/jp-journals-10008-1211"},{"key":"bibr9-0300060519847376","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2014.946"},{"key":"bibr10-0300060519847376","doi-asserted-by":"publisher","DOI":"10.1097\/ICB.0b013e3181c59973"},{"key":"bibr11-0300060519847376","first-page":"217","volume":"50","author":"Kumar A","year":"2002","journal-title":"Indian J Ophthalmol"},{"key":"bibr12-0300060519847376","doi-asserted-by":"publisher","DOI":"10.1186\/s40662-016-0055-5"},{"key":"bibr13-0300060519847376","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.76.2.109"},{"key":"bibr14-0300060519847376","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2014.126"},{"key":"bibr15-0300060519847376","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-09675-z"},{"key":"bibr16-0300060519847376","doi-asserted-by":"publisher","DOI":"10.1016\/j.oftal.2014.11.011"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300060519847376","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0300060519847376","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300060519847376","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:51:23Z","timestamp":1777459883000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0300060519847376"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,13]]},"references-count":16,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2020,8]]}},"alternative-id":["10.1177\/0300060519847376"],"URL":"https:\/\/doi.org\/10.1177\/0300060519847376","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5,13]]},"article-number":"0300060519847376"}}