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We also analyzed clinicopathological and follow-up data.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Our results showed that the rate of serum\n                      <jats:italic toggle=\"yes\">RASFF10<\/jats:italic>\n                      promoter methylation among patients with GC (49\/100) was higher than in those with CAG (1\/50) or HC (0\/45). Moreover, the\n                      <jats:italic toggle=\"yes\">RASSF10<\/jats:italic>\n                      methylation status was consistent between serum and tumor tissues. GC patients with serum\n                      <jats:italic toggle=\"yes\">RASSF10<\/jats:italic>\n                      promoter methylation had significantly shorter overall survival and disease-free survival times than GC patients without serum\n                      <jats:italic toggle=\"yes\">RASSF10<\/jats:italic>\n                      promoter methylation. Multivariable Cox regression analysis showed that serum\n                      <jats:italic toggle=\"yes\">RASSF10<\/jats:italic>\n                      promoter methylation and lymph node metastasis both correlated with reduced survival in GC patients.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Detection of the serum\n                      <jats:italic toggle=\"yes\">RASSF10<\/jats:italic>\n                      methylation status by MSP is feasible as a diagnostic and prognostic indicator of GC.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0300060519848924","type":"journal-article","created":{"date-parts":[[2019,5,23]],"date-time":"2019-05-23T05:25:27Z","timestamp":1558589127000},"page":"2890-2900","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Predictive value of the serum\n                    <i>RASSF10<\/i>\n                    promoter methylation status in gastric cancer"],"prefix":"10.1177","volume":"47","author":[{"given":"Yilin","family":"Hu","sequence":"first","affiliation":[{"name":"Department of Gastrointestinal Surgery, Affiliated Hospital of Nantong University, Nantong, China"},{"name":"Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery, Affiliated Hospital of Nantong University, Nantong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Feng","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery, Affiliated Hospital of Nantong University, Nantong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery, Affiliated Hospital of Nantong University, Nantong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Pathology, Affiliated Hospital of Nantong University, Nantong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yibing","family":"Guo","sequence":"additional","affiliation":[{"name":"Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qinsheng","family":"Mao","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery, Affiliated Hospital of Nantong University, Nantong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0137-7331","authenticated-orcid":false,"given":"Wanjiang","family":"Xue","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery, Affiliated Hospital of Nantong University, Nantong, China"},{"name":"Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,5,23]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21387"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21338"},{"key":"e_1_3_3_4_2","first-page":"181","article-title":"Circulating nucleic acids (CNAs) and cancer\u2014a survey.","volume":"1775","author":"Fleischhacker M","year":"2007","unstructured":"Fleischhacker M, Schmidt B. 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