{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T22:44:16Z","timestamp":1786747456401,"version":"build-2736575974"},"reference-count":29,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2019,6,24]],"date-time":"2019-06-24T00:00:00Z","timestamp":1561334400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Polymeric (Hem-o-lok) clips represent a novel technique with which to ligate the appendiceal stump following laparoscopic appendectomy. We compared the outcomes of using polymeric clips versus endostaplers for complicated and uncomplicated appendicitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Six hundred seventy-three consecutive patients undergoing laparoscopic appendectomy with polymeric clips or endostaplers for acute appendicitis were assessed. The primary outcome was the incidence of intra-abdominal abscesses. Predictors of postoperative intra-abdominal abscesses were calculated using univariate and multivariate analyses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Polymeric clips were used in 65% of patients and endostaplers were used in 35%. Hem-o-lok clips were not only applied in patients with uncomplicated appendicitis (83%), but also in those with complicated appendicitis (26%). The frequency of intra-abdominal abscesses using polymeric clips and endostaplers was similar in both patients with uncomplicated appendicitis (1% vs. 3%, respectively) and complicated appendicitis (2% vs. 6%, respectively). The univariate and multivariate analyses showed that the stump closure technique was not a risk factor for postoperative abscesses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Closure of the appendiceal stump using the nonabsorbable Hem-o-lok ligation system in patients with both uncomplicated and complicated appendicitis is a safe alternative to the application of endostaplers.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0300060519856154","type":"journal-article","created":{"date-parts":[[2019,6,25]],"date-time":"2019-06-25T10:18:03Z","timestamp":1561457883000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":19,"title":["Appendiceal stump closure with polymeric clips is a reliable alternative to endostaplers"],"prefix":"10.1177","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0884-9493","authenticated-orcid":false,"given":"Raphael","family":"Vuille-dit-Bille","sequence":"first","affiliation":[{"name":"Department of Visceral and Thoracic Surgery, Cantonal Hospital Winterthur, Winterthur, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3398-7385","authenticated-orcid":false,"given":"Christopher","family":"Soll","sequence":"additional","affiliation":[{"name":"Department of Visceral and Thoracic Surgery, Cantonal Hospital Winterthur, Winterthur, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Mazel","sequence":"additional","affiliation":[{"name":"Department of Visceral and Thoracic Surgery, Cantonal Hospital Winterthur, Winterthur, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8125-9986","authenticated-orcid":false,"given":"Ralph F.","family":"Staerkle","sequence":"additional","affiliation":[{"name":"Department of Visceral and Thoracic Surgery, Cantonal Hospital Winterthur, Winterthur, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Breitenstein","sequence":"additional","affiliation":[{"name":"Department of Visceral and Thoracic Surgery, Cantonal Hospital Winterthur, Winterthur, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,6,24]]},"reference":[{"key":"bibr1-0300060519856154","doi-asserted-by":"publisher","DOI":"10.1159\/000447647"},{"key":"bibr2-0300060519856154","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-016-4957-z"},{"issue":"10","key":"bibr3-0300060519856154","first-page":"CD001546","author":"Sauerland 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