{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T16:08:07Z","timestamp":1782835687745,"version":"3.54.5"},"reference-count":21,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2019,9,10]],"date-time":"2019-09-10T00:00:00Z","timestamp":1568073600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2019,9,10]],"date-time":"2019-09-10T00:00:00Z","timestamp":1568073600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"the Key Research and Development Program of Anhui province","award":["(no. 2019ZQ002)."],"award-info":[{"award-number":["(no. 2019ZQ002)."]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Nonalcoholic Wernicke\u2019s encephalopathy (WE) is a devastating neuropsychiatric syndrome caused by thiamine deficiency. Although many case reports on WE have been published, more studies are required to guide the diagnosis and treatment of nonalcoholic WE.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively studied patients who were diagnosed with WE in our hospital. Data on demographics, possible causes, phenomenology, and diagnostic and treatment delays were abstracted from medical records by chart reviews.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Seventeen patients were diagnosed with nonalcoholic WE. Nonalcoholic WE had many causes, such as gastrointestinal surgery, gastrointestinal tract diseases, vomiting, and psychiatric diseases. Most patients presented with abnormal mental symptoms, including those in a coma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In summary, we recommend using operational criteria to diagnose and treat nonalcoholic WE as early as possible to avoid misdiagnosis and treatment delays. Nonalcoholic WE remains a clinical diagnosis, and certain examinations are helpful for this diagnosis, such as measuring serum thiamine concentrations. We should focus on patients who present with abnormal mental symptoms, even those in a coma, and administer parenteral thiamine before any carbohydrate to reduce the high frequency of residual morbidity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0300060519870951","type":"journal-article","created":{"date-parts":[[2019,9,10]],"date-time":"2019-09-10T05:31:51Z","timestamp":1568093511000},"page":"4886-4894","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":15,"title":["Nonalcoholic Wernicke\u2019s encephalopathy: a retrospective study of 17 cases"],"prefix":"10.1177","volume":"47","author":[{"given":"Hongzhen","family":"Yin","sequence":"first","affiliation":[{"name":"Department of Critical Care Medicine, Research Center for Functional Maintenance and Reconstruction of Viscera, <!---->Wannan Medical College<!----> First Affiliated Hospital, Yijishan Hospital, Wuhu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiancheng","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Research Center for Functional Maintenance and Reconstruction of Viscera, <!---->Wannan Medical College<!----> First Affiliated Hospital, Yijishan Hospital, Wuhu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingya","family":"Cao","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Research Center for Functional Maintenance and Reconstruction of Viscera, <!---->Wannan Medical College<!----> First Affiliated Hospital, Yijishan Hospital, Wuhu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yupeng","family":"Qi","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Research Center for Functional Maintenance and Reconstruction of Viscera, <!---->Wannan Medical College<!----> First Affiliated Hospital, Yijishan Hospital, Wuhu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2475-4718","authenticated-orcid":false,"given":"Tao","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Research Center for Functional Maintenance and Reconstruction of Viscera, <!---->Wannan Medical College<!----> First Affiliated Hospital, Yijishan Hospital, Wuhu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weihua","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Research Center for Functional Maintenance and Reconstruction of Viscera, <!---->Wannan Medical College<!----> First Affiliated Hospital, Yijishan Hospital, Wuhu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,9,10]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1177\/0884533614561793"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/alcalc\/agm144"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.accpm.2014.09.005"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1177\/1971400915598080"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.07.3959"},{"key":"e_1_3_4_7_2","article-title":"Wernicke's encephalopathy in a patient with gastric carcinoma: a diagnosis not to miss","volume":"2014","author":"Kudru CU","year":"2014","unstructured":"Kudru CU, Nagiri SK, Rao S. 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